HCSGD entry for RBM8A
1. General information
| Official gene symbol | RBM8A |
|---|---|
| Entrez ID | 9939 |
| Gene full name | RNA binding motif protein 8A |
| Other gene symbols | BOV-1A BOV-1B BOV-1C C1DELq21.1 DEL1q21.1 MDS014 RBM8 RBM8B TAR Y14 ZNRP ZRNP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0000184 | Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | IMP TAS | biological_process |
| GO:0000381 | Regulation of alternative mRNA splicing, via spliceosome | IMP | biological_process |
| GO:0000398 | MRNA splicing, via spliceosome | IC TAS | biological_process |
| GO:0003723 | RNA binding | NAS | molecular_function |
| GO:0003729 | MRNA binding | NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA NAS | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | NAS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006369 | Termination of RNA polymerase II transcription | TAS | biological_process |
| GO:0006406 | MRNA export from nucleus | TAS | biological_process |
| GO:0006417 | Regulation of translation | IEA | biological_process |
| GO:0008380 | RNA splicing | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016070 | RNA metabolic process | TAS | biological_process |
| GO:0016071 | MRNA metabolic process | TAS | biological_process |
| GO:0016607 | Nuclear speck | IEA | cellular_component |
| GO:0031124 | MRNA 3'-end processing | TAS | biological_process |
| GO:0035145 | Exon-exon junction complex | IDA | cellular_component |
| GO:0071013 | Catalytic step 2 spliceosome | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8101003267 | 0.1147992326 | 0.9999902473 | 0.6492405539 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0444338702 |
| GSE13712_SHEAR | Down | -0.1136486991 |
| GSE13712_STATIC | Down | -0.1182860317 |
| GSE19018 | Down | -0.8451958434 |
| GSE19899_A1 | Down | -0.0035847616 |
| GSE19899_A2 | Down | -0.3914001948 |
| PubMed_21979375_A1 | Down | -0.9713654456 |
| PubMed_21979375_A2 | Down | -0.3410701572 |
| GSE35957 | Up | 0.0616749724 |
| GSE36640 | Down | -0.1522628125 |
| GSE54402 | Up | 0.0215051538 |
| GSE9593 | Down | -0.1297561961 |
| GSE43922 | Down | -0.1260981070 |
| GSE24585 | Up | 0.0433281151 |
| GSE37065 | Down | -0.0027195014 |
| GSE28863_A1 | Up | 0.3126655854 |
| GSE28863_A2 | Up | 0.7000784606 |
| GSE28863_A3 | Up | 0.2976167811 |
| GSE28863_A4 | Down | -0.0268853961 |
| GSE48662 | Down | -0.2545262488 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016487 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016487 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-340-5p | MIMAT0004692 | MIRT019607 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036981 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037447 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040350 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040716 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-148b-3p | MIMAT0000759 | MIRT043578 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045184 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051599 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-125b-5p | MIMAT0000423 | NA | hsa-miR-125b | 18056640 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
