HCSGD entry for MAFB
1. General information
| Official gene symbol | MAFB |
|---|---|
| Entrez ID | 9935 |
| Gene full name | v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian) |
| Other gene symbols | KRML MCTO |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005667 | Transcription factor complex | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0007379 | Segment specification | IEA | biological_process |
| GO:0007423 | Sensory organ development | TAS | biological_process |
| GO:0007585 | Respiratory gaseous exchange | IEA | biological_process |
| GO:0008134 | Transcription factor binding | IDA | molecular_function |
| GO:0021571 | Rhombomere 5 development | IEA | biological_process |
| GO:0021572 | Rhombomere 6 development | IEA | biological_process |
| GO:0033077 | T cell differentiation in thymus | IEA | biological_process |
| GO:0035284 | Brain segmentation | IEA | biological_process |
| GO:0042472 | Inner ear morphogenesis | IEA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0045647 | Negative regulation of erythrocyte differentiation | IDA | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0048538 | Thymus development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0045087573 | 0.1707525930 | 0.1782794074 | 0.7995692937 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2433774018 |
| GSE13712_SHEAR | Down | -1.8496012311 |
| GSE13712_STATIC | Down | -2.0375235205 |
| GSE19018 | Up | 0.0140237347 |
| GSE19899_A1 | Up | 0.1830504110 |
| GSE19899_A2 | Up | 2.3814527897 |
| PubMed_21979375_A1 | Up | 1.1211022848 |
| PubMed_21979375_A2 | Up | 1.2403719922 |
| GSE35957 | Down | -1.1027172987 |
| GSE36640 | Up | 0.7420358858 |
| GSE54402 | Up | 1.4114365219 |
| GSE9593 | Down | -0.1763261371 |
| GSE43922 | Up | 0.0275441049 |
| GSE24585 | Up | 0.4532118713 |
| GSE37065 | Up | 0.6619753528 |
| GSE28863_A1 | Up | 0.8370260066 |
| GSE28863_A2 | Up | 0.2908631914 |
| GSE28863_A3 | Up | 0.1347028331 |
| GSE28863_A4 | Down | -0.1565520922 |
| GSE48662 | Up | 0.3245492435 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-130a-3p | MIMAT0000425 | MIRT001141 | Luciferase reporter assay//Reporter assay | Functional MTI | 16549775 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT004507 | Microarray | Functional MTI (Weak) | 19193853 |
| hsa-miR-135b-5p | MIMAT0000758 | MIRT005442 | Luciferase reporter assay//Microarray//qRT-PCR | Functional MTI | 20981674 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT016975 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-130a-3p | MIMAT0000425 | NA | hsa-miR-130a | 16549775 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
