HCSGD entry for HELZ
1. General information
| Official gene symbol | HELZ |
|---|---|
| Entrez ID | 9931 |
| Gene full name | helicase with zinc finger |
| Other gene symbols | DHRC DRHC HUMORF5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004386 | Helicase activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1705366893 | 0.2379055735 | 0.8127279015 | 0.9386378297 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.7914535329 |
| GSE13712_SHEAR | Up | 0.5250624636 |
| GSE13712_STATIC | Up | 0.4468683412 |
| GSE19018 | Up | 0.2140789380 |
| GSE19899_A1 | Down | -0.2086804312 |
| GSE19899_A2 | Down | -0.1095690054 |
| PubMed_21979375_A1 | Down | -0.0969489993 |
| PubMed_21979375_A2 | Up | 0.1319911708 |
| GSE35957 | Up | 0.0621698496 |
| GSE36640 | Up | 0.2343185281 |
| GSE54402 | Down | -0.1824127323 |
| GSE9593 | Down | -0.3478127620 |
| GSE43922 | Down | -0.1800105259 |
| GSE24585 | Up | 0.5096262960 |
| GSE37065 | Down | -0.1021605675 |
| GSE28863_A1 | Up | 0.7996232494 |
| GSE28863_A2 | Up | 0.5651357599 |
| GSE28863_A3 | Down | -0.5080692129 |
| GSE28863_A4 | Down | -0.0950207458 |
| GSE48662 | Down | -0.1229764029 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027127 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031728 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-130b-5p | MIMAT0004680 | MIRT038308 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045007 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
