HCSGD entry for LPGAT1
1. General information
| Official gene symbol | LPGAT1 |
|---|---|
| Entrez ID | 9926 |
| Gene full name | lysophosphatidylglycerol acyltransferase 1 |
| Other gene symbols | FAM34A FAM34A1 NET8 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003674 | Molecular_function | ND | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006644 | Phospholipid metabolic process | TAS | biological_process |
| GO:0008150 | Biological_process | ND | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016746 | Transferase activity, transferring acyl groups | IEA | molecular_function |
| GO:0036148 | Phosphatidylglycerol acyl-chain remodeling | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046474 | Glycerophospholipid biosynthetic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9820647164 | 0.0074521561 | 0.9999902473 | 0.1728177974 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3658992581 |
| GSE13712_SHEAR | Down | -0.4591475794 |
| GSE13712_STATIC | Down | -0.3127333572 |
| GSE19018 | Down | -0.0606591535 |
| GSE19899_A1 | Down | -1.2302251041 |
| GSE19899_A2 | Down | -0.9410473927 |
| PubMed_21979375_A1 | Down | -0.4081447040 |
| PubMed_21979375_A2 | Down | -0.5664801093 |
| GSE35957 | Up | 0.3498474814 |
| GSE36640 | Up | 0.0005249653 |
| GSE54402 | Down | -0.9305448934 |
| GSE9593 | Up | 0.2455344822 |
| GSE43922 | Down | -0.4246103818 |
| GSE24585 | Down | -0.1835915617 |
| GSE37065 | Down | -0.1527418176 |
| GSE28863_A1 | Down | -0.2124617342 |
| GSE28863_A2 | Down | -0.0684256309 |
| GSE28863_A3 | Down | -0.5608247701 |
| GSE28863_A4 | Down | -0.2562915305 |
| GSE48662 | Up | 0.7334716345 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020116 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020554 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-181a-5p | MIMAT0000256 | MIRT025088 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030680 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031111 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032249 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041219 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
