HCSGD entry for G3BP2
1. General information
| Official gene symbol | G3BP2 |
|---|---|
| Entrez ID | 9908 |
| Gene full name | GTPase activating protein (SH3 domain) binding protein 2 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA NAS | cellular_component |
| GO:0006810 | Transport | IEA | biological_process |
| GO:0007253 | Cytoplasmic sequestering of NF-kappaB | NAS | biological_process |
| GO:0007265 | Ras protein signal transduction | NAS | biological_process |
| GO:0030159 | Receptor signaling complex scaffold activity | NAS | molecular_function |
| GO:0051028 | MRNA transport | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7018774325 | 0.3329685650 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0105581561 |
| GSE13712_SHEAR | Up | 0.1753003963 |
| GSE13712_STATIC | Up | 0.0455648130 |
| GSE19018 | Down | -0.1251417411 |
| GSE19899_A1 | Up | 0.3049255612 |
| GSE19899_A2 | Down | -0.0055590920 |
| PubMed_21979375_A1 | Down | -0.4151315446 |
| PubMed_21979375_A2 | Down | -0.1074914423 |
| GSE35957 | Up | 0.2452459104 |
| GSE36640 | Up | 0.0051354225 |
| GSE54402 | Up | 0.0193319650 |
| GSE9593 | Up | 0.1006712246 |
| GSE43922 | Down | -0.0405791782 |
| GSE24585 | Up | 0.3046602942 |
| GSE37065 | Up | 0.1111992621 |
| GSE28863_A1 | Down | -0.0829387456 |
| GSE28863_A2 | Down | -0.0731980577 |
| GSE28863_A3 | Down | -0.6520910885 |
| GSE28863_A4 | Down | -0.2466906496 |
| GSE48662 | Down | -0.1309467751 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-200a-3p | MIMAT0000682 | MIRT000772 | Microarray//Northern blot | Functional MTI (Weak) | 16331254 |
| hsa-miR-361-5p | MIMAT0000703 | MIRT020092 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022458 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-1 | MIMAT0000416 | MIRT023607 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025342 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027093 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029217 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031551 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-484 | MIMAT0002174 | MIRT042053 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049526 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-4326 | MIMAT0016888 | MIRT052841 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
