HCSGD entry for MAGI2

1. General information

Official gene symbolMAGI2
Entrez ID9863
Gene full namemembrane associated guanylate kinase, WW and PDZ domain containing 2
Other gene symbolsACVRIP1 AIP-1 AIP1 ARIP1 MAGI-2 SSCAM
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002092Positive regulation of receptor internalizationIDAbiological_process
GO:0003402Planar cell polarity pathway involved in axis elongationNASbiological_process
GO:0004871Signal transducer activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005770Late endosomeISScellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0005923Tight junctionIDAcellular_component
GO:0008285Negative regulation of cell proliferationISSbiological_process
GO:0010976Positive regulation of neuron projection developmentISSbiological_process
GO:0014069Postsynaptic densityISScellular_component
GO:0016482Cytoplasmic transportISSbiological_process
GO:0019902Phosphatase bindingIPImolecular_function
GO:0030159Receptor signaling complex scaffold activityIDAmolecular_function
GO:0030336Negative regulation of cell migrationISSbiological_process
GO:0030425DendriteISScellular_component
GO:0031697Beta-1 adrenergic receptor bindingIPImolecular_function
GO:0032516Positive regulation of phosphoprotein phosphatase activityIDAbiological_process
GO:0032926Negative regulation of activin receptor signaling pathwayISSbiological_process
GO:0036057Slit diaphragmISScellular_component
GO:0038180Nerve growth factor signaling pathwayISSbiological_process
GO:0043113Receptor clusteringISSbiological_process
GO:0043234Protein complexISScellular_component
GO:0045202SynapseISScellular_component
GO:0046332SMAD bindingISSmolecular_function
GO:0048471Perinuclear region of cytoplasmISScellular_component
GO:0051291Protein heterooligomerizationISSbiological_process
GO:0051898Negative regulation of protein kinase B signalingIDAbiological_process
GO:0060395SMAD protein signal transductionISSbiological_process
GO:0070699Type II activin receptor bindingISSmolecular_function
GO:0071850Mitotic cell cycle arrestISSbiological_process
GO:0072015Glomerular visceral epithelial cell developmentISSbiological_process
GO:1990090Cellular response to nerve growth factor stimulusISSbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.23769309680.07705580340.92330578510.5246384894

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0838379107
GSE13712_SHEARDown-0.3659929524
GSE13712_STATICDown-0.3086034098
GSE19018Up0.8335998515
GSE19899_A1Down-0.3625643001
GSE19899_A2Down-0.3939457403
PubMed_21979375_A1Down-1.0852558953
PubMed_21979375_A2Down-0.4898667769
GSE35957Up0.6007463127
GSE36640Up0.3794472554
GSE54402Down-0.2604740380
GSE9593Up0.2823542001
GSE43922Down-1.1796053075
GSE24585Up1.3090126265
GSE37065Up0.0833760220
GSE28863_A1Up0.1074194784
GSE28863_A2Up0.0963637136
GSE28863_A3Down-0.0160752946
GSE28863_A4Down-0.0673605826
GSE48662Down-0.1535138904

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.