HCSGD entry for GINS1
1. General information
| Official gene symbol | GINS1 |
|---|---|
| Entrez ID | 9837 |
| Gene full name | GINS complex subunit 1 (Psf1 homolog) |
| Other gene symbols | PSF1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0001833 | Inner cell mass cell proliferation | IEA | biological_process |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006271 | DNA strand elongation involved in DNA replication | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9815663539 | 0.0000196915 | 0.9999902473 | 0.0084212121 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.6779962986 |
| GSE13712_SHEAR | Up | 0.1136570963 |
| GSE13712_STATIC | Down | -0.3897226973 |
| GSE19018 | Down | -0.6733705862 |
| GSE19899_A1 | Down | -1.9129915029 |
| GSE19899_A2 | Down | -3.1871986887 |
| PubMed_21979375_A1 | Down | -2.1482872459 |
| PubMed_21979375_A2 | Down | -4.7160790510 |
| GSE35957 | Down | -3.6987742117 |
| GSE36640 | Down | -3.8612958535 |
| GSE54402 | Down | -0.5374679519 |
| GSE9593 | Down | -2.0259152666 |
| GSE43922 | Down | -1.8187860574 |
| GSE24585 | Down | -0.3816713763 |
| GSE37065 | Down | -0.3394264245 |
| GSE28863_A1 | Down | -0.5604439078 |
| GSE28863_A2 | Up | 0.5913542471 |
| GSE28863_A3 | Down | -0.2902010057 |
| GSE28863_A4 | Up | 0.3888866996 |
| GSE48662 | Down | -1.1295407826 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-186-5p | MIMAT0000456 | MIRT021144 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025773 | Microarray | Functional MTI (Weak) | 19073608 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029528 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-18a-3p | MIMAT0002891 | MIRT040758 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
