HCSGD entry for GIT2


1. General information

Official gene symbolGIT2
Entrez ID9815
Gene full nameG protein-coupled receptor kinase interacting ArfGAP 2
Other gene symbolsCAT-2 CAT2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005654NucleoplasmIDAcellular_component
GO:0008060ARF GTPase activator activityIEAmolecular_function
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0008277Regulation of G-protein coupled receptor protein signaling pathwayTASbiological_process
GO:0032312Regulation of ARF GTPase activityIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.15296769120.95212651870.77985008721.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1503647024
GSE13712_SHEARDown-0.0029917766
GSE13712_STATICUp0.0175491720
GSE19018Up0.1167635035
GSE19899_A1Up0.0320797028
GSE19899_A2Up0.1261817094
PubMed_21979375_A1Up0.2906011438
PubMed_21979375_A2Up0.5932478905
GSE35957Up0.2855614377
GSE36640Down-0.1395795245
GSE54402Up0.0440715186
GSE9593Up0.1065944117
GSE43922Down-0.0616714891
GSE24585Up0.3746700250
GSE37065Down-0.0644334673
GSE28863_A1Up0.5385405998
GSE28863_A2Up0.4789233111
GSE28863_A3Down-0.1418693081
GSE28863_A4Down-0.0302320946
GSE48662Down-0.0553029991

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT022651MicroarrayFunctional MTI (Weak)18668037
hsa-miR-26a-5pMIMAT0000082MIRT050071CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.