HCSGD entry for GIT2
1. General information
| Official gene symbol | GIT2 |
|---|---|
| Entrez ID | 9815 |
| Gene full name | G protein-coupled receptor kinase interacting ArfGAP 2 |
| Other gene symbols | CAT-2 CAT2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005654 | Nucleoplasm | IDA | cellular_component |
| GO:0008060 | ARF GTPase activator activity | IEA | molecular_function |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0008277 | Regulation of G-protein coupled receptor protein signaling pathway | TAS | biological_process |
| GO:0032312 | Regulation of ARF GTPase activity | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1529676912 | 0.9521265187 | 0.7798500872 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1503647024 |
| GSE13712_SHEAR | Down | -0.0029917766 |
| GSE13712_STATIC | Up | 0.0175491720 |
| GSE19018 | Up | 0.1167635035 |
| GSE19899_A1 | Up | 0.0320797028 |
| GSE19899_A2 | Up | 0.1261817094 |
| PubMed_21979375_A1 | Up | 0.2906011438 |
| PubMed_21979375_A2 | Up | 0.5932478905 |
| GSE35957 | Up | 0.2855614377 |
| GSE36640 | Down | -0.1395795245 |
| GSE54402 | Up | 0.0440715186 |
| GSE9593 | Up | 0.1065944117 |
| GSE43922 | Down | -0.0616714891 |
| GSE24585 | Up | 0.3746700250 |
| GSE37065 | Down | -0.0644334673 |
| GSE28863_A1 | Up | 0.5385405998 |
| GSE28863_A2 | Up | 0.4789233111 |
| GSE28863_A3 | Down | -0.1418693081 |
| GSE28863_A4 | Down | -0.0302320946 |
| GSE48662 | Down | -0.0553029991 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022651 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-26a-5p | MIMAT0000082 | MIRT050071 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
