HCSGD entry for IP6K1
1. General information
| Official gene symbol | IP6K1 |
|---|---|
| Entrez ID | 9807 |
| Gene full name | inositol hexakisphosphate kinase 1 |
| Other gene symbols | IHPK1 PiUS |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000832 | Inositol hexakisphosphate 5-kinase activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0008440 | Inositol-1,4,5-trisphosphate 3-kinase activity | IEA | molecular_function |
| GO:0043647 | Inositol phosphate metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046854 | Phosphatidylinositol phosphorylation | IDA | biological_process |
| GO:0052723 | Inositol hexakisphosphate 1-kinase activity | IEA | molecular_function |
| GO:0052724 | Inositol hexakisphosphate 3-kinase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0807412104 | 0.7974167851 | 0.5987801972 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0920797013 |
| GSE13712_SHEAR | Down | -0.2450814738 |
| GSE13712_STATIC | Down | -0.0064602398 |
| GSE19018 | Down | -0.0100496962 |
| GSE19899_A1 | Up | 0.2131137156 |
| GSE19899_A2 | Up | 0.2226211784 |
| PubMed_21979375_A1 | Up | 1.0912617757 |
| PubMed_21979375_A2 | Up | 1.0704155515 |
| GSE35957 | Down | -0.1288857125 |
| GSE36640 | Up | 0.2475133781 |
| GSE54402 | Up | 0.3144938849 |
| GSE9593 | Down | -0.2595221242 |
| GSE43922 | Up | 0.1353760990 |
| GSE24585 | Up | 0.2593754986 |
| GSE37065 | Down | -0.1329114367 |
| GSE28863_A1 | Up | 0.4810009787 |
| GSE28863_A2 | Up | 0.1643629601 |
| GSE28863_A3 | Up | 0.0298973875 |
| GSE28863_A4 | Down | -0.3136774361 |
| GSE48662 | Up | 0.2116647441 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-877-3p | MIMAT0004950 | MIRT036940 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037697 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125a-5p | MIMAT0000443 | MIRT045778 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT046105 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT048829 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7c-5p | MIMAT0000064 | MIRT051729 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT051881 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
