HCSGD entry for SCRN1
1. General information
| Official gene symbol | SCRN1 |
|---|---|
| Entrez ID | 9805 |
| Gene full name | secernin 1 |
| Other gene symbols | SES1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003674 | Molecular_function | ND | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0006887 | Exocytosis | ISS | biological_process |
| GO:0016805 | Dipeptidase activity | IEA | molecular_function |
| GO:0031965 | Nuclear membrane | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2399635044 | 0.0184055773 | 0.9259134418 | 0.2655993421 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2845042554 |
| GSE13712_SHEAR | Up | 0.3059570936 |
| GSE13712_STATIC | Up | 0.0436728761 |
| GSE19018 | Up | 0.7426360261 |
| GSE19899_A1 | Down | -1.5162657588 |
| GSE19899_A2 | Down | -0.7925689421 |
| PubMed_21979375_A1 | Down | -1.5267111553 |
| PubMed_21979375_A2 | Down | -1.0039861365 |
| GSE35957 | Up | 0.4818545236 |
| GSE36640 | Up | 0.0948766531 |
| GSE54402 | Up | 0.0675053953 |
| GSE9593 | Up | 0.4461556442 |
| GSE43922 | Down | -1.1400395889 |
| GSE24585 | Up | 0.5197927204 |
| GSE37065 | Down | -0.0185830329 |
| GSE28863_A1 | Down | -0.2023363963 |
| GSE28863_A2 | Up | 0.0870118419 |
| GSE28863_A3 | Down | -1.0374071015 |
| GSE28863_A4 | Up | 0.2134956156 |
| GSE48662 | Down | -0.0158256372 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-21-5p | MIMAT0000076 | MIRT031060 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032457 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-320c | MIMAT0005793 | MIRT036155 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-26a-5p | MIMAT0000082 | MIRT050057 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
