HCSGD entry for ZFYVE16
1. General information
| Official gene symbol | ZFYVE16 |
|---|---|
| Entrez ID | 9765 |
| Gene full name | zinc finger, FYVE domain containing 16 |
| Other gene symbols | ENDOFIN PPP1R69 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005545 | 1-phosphatidylinositol binding | IDA | molecular_function |
| GO:0005547 | Phosphatidylinositol-3,4,5-trisphosphate binding | IDA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005769 | Early endosome | IDA | cellular_component |
| GO:0006622 | Protein targeting to lysosome | IMP | biological_process |
| GO:0007165 | Signal transduction | NAS | biological_process |
| GO:0008565 | Protein transporter activity | IMP | molecular_function |
| GO:0016050 | Vesicle organization | NAS | biological_process |
| GO:0016197 | Endosomal transport | IMP | biological_process |
| GO:0030100 | Regulation of endocytosis | TAS | biological_process |
| GO:0030509 | BMP signaling pathway | TAS | biological_process |
| GO:0031901 | Early endosome membrane | TAS | cellular_component |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2271948254 | 0.2827899130 | 0.9085965208 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0595142078 |
| GSE13712_SHEAR | Up | 0.1134465405 |
| GSE13712_STATIC | Up | 0.1678091480 |
| GSE19018 | Down | -0.2064402438 |
| GSE19899_A1 | Up | 0.0150062140 |
| GSE19899_A2 | Down | -0.2829876571 |
| PubMed_21979375_A1 | Up | 1.0369822664 |
| PubMed_21979375_A2 | Up | 0.0546127653 |
| GSE35957 | Down | -0.0656966032 |
| GSE36640 | Down | -0.2379778316 |
| GSE54402 | Up | 0.0907305471 |
| GSE9593 | Down | -0.3381648455 |
| GSE43922 | Up | 0.6861064550 |
| GSE24585 | Up | 0.3260202159 |
| GSE37065 | Up | 0.2923827224 |
| GSE28863_A1 | Up | 0.2283528055 |
| GSE28863_A2 | Up | 0.3132885426 |
| GSE28863_A3 | Down | -0.7218798852 |
| GSE28863_A4 | Down | -0.4485066512 |
| GSE48662 | Down | -0.2527137628 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-21-5p | MIMAT0000076 | MIRT030907 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039852 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-106b-5p | MIMAT0000680 | MIRT044303 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046581 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049461 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
