HCSGD entry for MLEC


1. General information

Official gene symbolMLEC
Entrez ID9761
Gene full namemalectin
Other gene symbolsKIAA0152
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005783Endoplasmic reticulumISScellular_component
GO:0005789Endoplasmic reticulum membraneTAScellular_component
GO:0006457Protein foldingTASbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0018279Protein N-linked glycosylation via asparagineTASbiological_process
GO:0030246Carbohydrate bindingISSmolecular_function
GO:0043687Post-translational protein modificationTASbiological_process
GO:0044267Cellular protein metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.37904697010.19664699670.99999024730.8585939957

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2759265469
GSE13712_SHEARDown-0.0990464651
GSE13712_STATICUp0.0673114182
GSE19018Down-0.1838088531
GSE19899_A1Down-0.5198308913
GSE19899_A2Down-0.1414789008
PubMed_21979375_A1Down-0.4820037034
PubMed_21979375_A2Up0.8529996933
GSE35957Down-0.8321255780
GSE36640Up0.1280403192
GSE54402Up0.4613057637
GSE9593Down-0.0275696541
GSE43922Down-0.0202944214
GSE24585Down-0.1558135513
GSE37065Down-0.2175843024
GSE28863_A1Up0.1724831613
GSE28863_A2Up0.5611653995
GSE28863_A3Down-0.5252746856
GSE28863_A4Up0.2401988821
GSE48662Down-0.1910516774

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-24-3pMIMAT0000080MIRT003889Luciferase reporter assayNon-Functional MTI15131085
hsa-miR-24-3pMIMAT0000080MIRT003889Reporter assay;Western blot;OtherFunctional MTI19748357
hsa-miR-375MIMAT0000728MIRT019896MicroarrayFunctional MTI (Weak)20215506
hsa-miR-124-3pMIMAT0000422MIRT022943MicroarrayFunctional MTI (Weak)18668037
hsa-miR-296-3pMIMAT0004679MIRT038439CLASHFunctional MTI (Weak)23622248
hsa-miR-25-3pMIMAT0000081MIRT050275CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.