HCSGD entry for PLCH2

1. General information

Official gene symbolPLCH2
Entrez ID9651
Gene full namephospholipase C, eta 2
Other gene symbolsPLC-eta2 PLCL4 PLCeta2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003674Molecular_functionNDmolecular_function
GO:0004435Phosphatidylinositol phospholipase C activityIEAmolecular_function
GO:0004629Phospholipase C activityIEAmolecular_function
GO:0004871Signal transducer activityIEAmolecular_function
GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005575Cellular_componentNDcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0006629Lipid metabolic processIEAbiological_process
GO:0008150Biological_processNDbiological_process
GO:0016042Lipid catabolic processIEAbiological_process
GO:0035556Intracellular signal transductionIEAbiological_process
GO:0043647Inositol phosphate metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046488Phosphatidylinositol metabolic processIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.24751331640.93144557200.93545827711.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0641020505
GSE13712_SHEARUp0.0224565419
GSE13712_STATICDown-0.0271581845
GSE19018Up0.2213629785
GSE19899_A1Down-0.1020769693
GSE19899_A2Up0.1099001382
PubMed_21979375_A1Up0.0506626534
PubMed_21979375_A2Down-0.3267756567
GSE35957Up0.2542529976
GSE36640Up0.1049872820
GSE54402Up0.0818734077
GSE9593Up0.0378351067
GSE43922Up0.0917503997
GSE24585Up0.1778032824
GSE37065Down-0.1834932853
GSE28863_A1Down-0.1106978023
GSE28863_A2Up0.1614817794
GSE28863_A3Up0.3042690956
GSE28863_A4Up0.1053191567
GSE48662Up0.7193242894

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029064MicroarrayFunctional MTI (Weak)19088304
hsa-miR-331-3pMIMAT0000760MIRT043301CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.