HCSGD entry for RALGPS1

1. General information

Official gene symbolRALGPS1
Entrez ID9649
Gene full nameRal GEF with PH domain and SH3 binding motif 1
Other gene symbolsRALGEF2 RALGPS1A
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005085Guanyl-nucleotide exchange factor activityIEA NASmolecular_function
GO:0005575Cellular_componentNDcellular_component
GO:0005622IntracellularIEAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0005886Plasma membraneIEAcellular_component
GO:0007264Small GTPase mediated signal transductionIEAbiological_process
GO:0008321Ral guanyl-nucleotide exchange factor activityIDAmolecular_function
GO:0032315Regulation of Ral GTPase activityIDAbiological_process
GO:0032318Regulation of Ras GTPase activityIDAbiological_process
GO:0032485Regulation of Ral protein signal transductionIDAbiological_process
GO:0035556Intracellular signal transductionNASbiological_process
GO:0043087Regulation of GTPase activityIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.81746090570.85424685230.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0498822658
GSE13712_SHEARDown-0.1853278955
GSE13712_STATICDown-0.0151439437
GSE19018Up0.1424208275
GSE19899_A1Up0.0750740744
GSE19899_A2Down-0.1505277016
PubMed_21979375_A1Down-0.1075208375
PubMed_21979375_A2Up0.0001493649
GSE35957Up0.0388624420
GSE36640Up0.1584079671
GSE54402Down-0.0687808256
GSE9593Down-0.0244511372
GSE43922Up0.0369255273
GSE24585Down-0.0080921312
GSE37065Down-0.1003016894
GSE28863_A1Down-0.0159046222
GSE28863_A2Up0.1780668636
GSE28863_A3Up0.1419428238
GSE28863_A4Up0.0597635025
GSE48662Down-0.0159417912

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.