HCSGD entry for MICAL2


1. General information

Official gene symbolMICAL2
Entrez ID9645
Gene full namemicrotubule associated monooxygenase, calponin and LIM domain containing 2
Other gene symbolsMICAL-2 MICAL2PV1 MICAL2PV2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003779Actin bindingISSmolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005856CytoskeletonIEAcellular_component
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0016709Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygenISSmolecular_function
GO:0019417Sulfur oxidationIEA ISSbiological_process
GO:0030042Actin filament depolymerizationISSbiological_process
GO:0055114Oxidation-reduction processISSbiological_process
GO:0071949FAD bindingISSmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.34658807800.13072574370.99999024730.6958204853

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.5564540203
GSE13712_SHEARUp0.0645088003
GSE13712_STATICUp0.2640471193
GSE19018Down-0.3739567394
GSE19899_A1Down-0.1516662940
GSE19899_A2Down-0.0975370561
PubMed_21979375_A1Down-0.1693600219
PubMed_21979375_A2Up0.0498452072
GSE35957Up0.4996888749
GSE36640Down-0.4492723620
GSE54402Up0.1939493455
GSE9593Up0.4318795774
GSE43922Down-0.0131886594
GSE24585Down-0.0385905304
GSE37065Down-1.0511605195
GSE28863_A1Up0.0644915864
GSE28863_A2Up0.8454677671
GSE28863_A3Down-0.2832606400
GSE28863_A4Up0.0985306262
GSE48662Up0.1219015011

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT022138MicroarrayFunctional MTI (Weak)18668037
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.