HCSGD entry for GNA14
1. General information
| Official gene symbol | GNA14 |
|---|---|
| Entrez ID | 9630 |
| Gene full name | guanine nucleotide binding protein (G protein), alpha 14 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001664 | G-protein coupled receptor binding | IBA | molecular_function |
| GO:0003924 | GTPase activity | IEA | molecular_function |
| GO:0004871 | Signal transducer activity | IBA | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005834 | Heterotrimeric G-protein complex | IBA | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007188 | Adenylate cyclase-modulating G-protein coupled receptor signaling pathway | IBA | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0030168 | Platelet activation | TAS | biological_process |
| GO:0031234 | Extrinsic component of cytoplasmic side of plasma membrane | IBA | cellular_component |
| GO:0031683 | G-protein beta/gamma-subunit complex binding | IBA | molecular_function |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0060158 | Phospholipase C-activating dopamine receptor signaling pathway | IBA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2358681775 | 0.6300335474 | 0.9196098800 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0792645431 |
| GSE13712_SHEAR | Down | -0.6649619277 |
| GSE13712_STATIC | Down | -0.2861603999 |
| GSE19018 | Up | 0.0181257196 |
| GSE19899_A1 | Up | 0.0693258761 |
| GSE19899_A2 | Up | 0.1273674435 |
| PubMed_21979375_A1 | Up | 0.0773098451 |
| PubMed_21979375_A2 | Up | 0.0709267048 |
| GSE35957 | Up | 1.0692022206 |
| GSE36640 | Up | 0.2160379102 |
| GSE54402 | Up | 0.0606561735 |
| GSE9593 | Up | 0.5358017190 |
| GSE43922 | Up | 0.0132665551 |
| GSE24585 | Down | -0.0372493270 |
| GSE37065 | Up | 0.0991869259 |
| GSE28863_A1 | Down | -0.0269961608 |
| GSE28863_A2 | Up | 0.1715634496 |
| GSE28863_A3 | Up | 0.0154818404 |
| GSE28863_A4 | Up | 0.0802805593 |
| GSE48662 | Up | 0.0876360886 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018573 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
