HCSGD entry for CELSR1

1. General information

Official gene symbolCELSR1
Entrez ID9620
Gene full namecadherin, EGF LAG seven-pass G-type receptor 1
Other gene symbolsCDHF9 FMI2 HFMI2 ME2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001736Establishment of planar polarityISSbiological_process
GO:0001764Neuron migrationIEAbiological_process
GO:0001843Neural tube closureISSbiological_process
GO:0001942Hair follicle developmentIEAbiological_process
GO:0004888Transmembrane signaling receptor activityNASmolecular_function
GO:0004930G-protein coupled receptor activityNASmolecular_function
GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005886Plasma membraneIEAcellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0007156Homophilic cell adhesionIEAbiological_process
GO:0007186G-protein coupled receptor signaling pathwayNASbiological_process
GO:0007218Neuropeptide signaling pathwayIEAbiological_process
GO:0007266Rho protein signal transductionIEAbiological_process
GO:0007417Central nervous system developmentNAS TASbiological_process
GO:0007626Locomotory behaviorIEAbiological_process
GO:0009952Anterior/posterior pattern specificationIEAbiological_process
GO:0016021Integral component of membraneIEA TAScellular_component
GO:0032956Regulation of actin cytoskeleton organizationIEAbiological_process
GO:0042060Wound healingIEAbiological_process
GO:0042249Establishment of planar polarity of embryonic epitheliumIEAbiological_process
GO:0042472Inner ear morphogenesisIEAbiological_process
GO:0045176Apical protein localizationIEAbiological_process
GO:0046983Protein dimerization activityNASmolecular_function
GO:0048105Establishment of body hair planar orientationIEAbiological_process
GO:0060488Orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesisIEAbiological_process
GO:0060489Planar dichotomous subdivision of terminal units involved in lung branching morphogenesisIEAbiological_process
GO:0060490Lateral sprouting involved in lung morphogenesisIEAbiological_process
GO:0090179Planar cell polarity pathway involved in neural tube closureIEAbiological_process
GO:0090251Protein localization involved in establishment of planar polarityIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.60166218990.75592277650.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0077328761
GSE13712_SHEARDown-0.8559620841
GSE13712_STATICDown-0.1644979519
GSE19018Down-0.0170978083
GSE19899_A1Up0.1212309001
GSE19899_A2Up0.1006367971
PubMed_21979375_A1Up0.0073652024
PubMed_21979375_A2Up0.1237482134
GSE35957Down-0.0724127176
GSE36640Down-0.0739548584
GSE54402Up0.1322956650
GSE9593Up0.0525063897
GSE43922Up0.0333290745
GSE24585Up0.2170203066
GSE37065Down-0.0778608702
GSE28863_A1Down-0.0550920717
GSE28863_A2Down-0.0227124634
GSE28863_A3Up0.3544879340
GSE28863_A4Up0.1400926274
GSE48662Up0.1481017358

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-615-3pMIMAT0003283MIRT040199CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049355CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.