HCSGD entry for GDA
1. General information
| Official gene symbol | GDA |
|---|---|
| Entrez ID | 9615 |
| Gene full name | guanine deaminase |
| Other gene symbols | CYPIN GUANASE NEDASIN |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005622 | Intracellular | TAS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006139 | Nucleobase-containing compound metabolic process | TAS | biological_process |
| GO:0006144 | Purine nucleobase metabolic process | TAS | biological_process |
| GO:0006147 | Guanine catabolic process | IEA | biological_process |
| GO:0006195 | Purine nucleotide catabolic process | TAS | biological_process |
| GO:0007399 | Nervous system development | TAS | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0008892 | Guanine deaminase activity | EXP IEA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0055086 | Nucleobase-containing small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0549493408 | 0.5457618973 | 0.5116105691 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0413777752 |
| GSE13712_SHEAR | Down | -0.0339913627 |
| GSE13712_STATIC | Down | -0.0127136286 |
| GSE19018 | Up | 0.2332459465 |
| GSE19899_A1 | Up | 0.2536680545 |
| GSE19899_A2 | Up | 0.5221979108 |
| PubMed_21979375_A1 | Up | 2.3626549211 |
| PubMed_21979375_A2 | Up | 0.8764714534 |
| GSE35957 | Up | 0.3027624645 |
| GSE36640 | Up | 0.0264473737 |
| GSE54402 | Up | 1.7725127369 |
| GSE9593 | Down | -0.1681061574 |
| GSE43922 | Up | 0.0125365483 |
| GSE24585 | Down | -0.1913603990 |
| GSE37065 | Down | -0.0502246578 |
| GSE28863_A1 | Down | -1.4511744307 |
| GSE28863_A2 | Down | -0.0719494531 |
| GSE28863_A3 | Up | 0.1500694932 |
| GSE28863_A4 | Down | -0.0133984026 |
| GSE48662 | Down | -0.0397336003 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022762 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
