HCSGD entry for PDIA4
1. General information
| Official gene symbol | PDIA4 |
|---|---|
| Entrez ID | 9601 |
| Gene full name | protein disulfide isomerase family A, member 4 |
| Other gene symbols | ERP70 ERP72 ERp-72 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003756 | Protein disulfide isomerase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005788 | Endoplasmic reticulum lumen | IEA | cellular_component |
| GO:0006662 | Glycerol ether metabolic process | IEA | biological_process |
| GO:0009306 | Protein secretion | TAS | biological_process |
| GO:0009986 | Cell surface | IDA | cellular_component |
| GO:0015035 | Protein disulfide oxidoreductase activity | IEA | molecular_function |
| GO:0042470 | Melanosome | IEA | cellular_component |
| GO:0045454 | Cell redox homeostasis | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8767215531 | 0.0100753999 | 0.9999902473 | 0.1989456864 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0640083531 |
| GSE13712_SHEAR | Down | -0.3242214552 |
| GSE13712_STATIC | Down | -0.4370728585 |
| GSE19018 | Up | 0.3626171384 |
| GSE19899_A1 | Down | -0.3974092094 |
| GSE19899_A2 | Down | -0.8318015520 |
| PubMed_21979375_A1 | Down | -1.2042830476 |
| PubMed_21979375_A2 | Down | -1.3820344770 |
| GSE35957 | Down | -0.8653720896 |
| GSE36640 | Down | -0.6335371386 |
| GSE54402 | Up | 0.1356863543 |
| GSE9593 | Down | -0.6201309098 |
| GSE43922 | Down | -0.1812312061 |
| GSE24585 | Up | 0.1190412908 |
| GSE37065 | Down | -0.0307331382 |
| GSE28863_A1 | Up | 0.1818022331 |
| GSE28863_A2 | Up | 0.8537598254 |
| GSE28863_A3 | Down | -0.7011955586 |
| GSE28863_A4 | Down | -0.1406919811 |
| GSE48662 | Down | -0.1774896353 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018114 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036839 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049739 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
