HCSGD entry for CREB5
1. General information
| Official gene symbol | CREB5 |
|---|---|
| Entrez ID | 9586 |
| Gene full name | cAMP responsive element binding protein 5 |
| Other gene symbols | CRE-BPA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001077 | RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription | IEA | molecular_function |
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IC IEA | cellular_component |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0045444 | Fat cell differentiation | IEA | biological_process |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0060612 | Adipose tissue development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5721722313 | 0.5956920558 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2080794503 |
| GSE13712_SHEAR | Up | 0.1913657874 |
| GSE13712_STATIC | Down | -0.2311201726 |
| GSE19018 | Up | 0.1352102857 |
| GSE19899_A1 | Down | -0.0050613201 |
| GSE19899_A2 | Up | 0.0448635495 |
| PubMed_21979375_A1 | Up | 0.2094586694 |
| PubMed_21979375_A2 | Down | -0.2023159630 |
| GSE35957 | Up | 0.0076187794 |
| GSE36640 | Down | -0.3587874833 |
| GSE54402 | Down | -0.2315626929 |
| GSE9593 | Up | 0.0529346353 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Up | 0.5263069815 |
| GSE28863_A2 | Up | 0.3757866413 |
| GSE28863_A3 | Up | 0.2450759374 |
| GSE28863_A4 | Up | 0.0590106814 |
| GSE48662 | Down | -0.1134886676 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-204-5p | MIMAT0000265 | MIRT006460 | Immunofluorescence//Microarray//qRT-PCR//Western blot | Functional MTI | 22523078 |
| hsa-miR-211-5p | MIMAT0000268 | MIRT006462 | Immunofluorescence//Microarray//qRT-PCR//Western blot | Functional MTI | 22523078 |
| hsa-miR-125a-5p | MIMAT0000443 | MIRT021286 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT025590 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-32-5p | MIMAT0000090 | MIRT028329 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
