HCSGD entry for APOBEC3B
1. General information
| Official gene symbol | APOBEC3B |
|---|---|
| Entrez ID | 9582 |
| Gene full name | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| Other gene symbols | A3B APOBEC1L ARCD3 ARP4 DJ742C19.2 PHRBNL bK150C2.2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0008152 | Metabolic process | IMP | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0010529 | Negative regulation of transposition | IDA | biological_process |
| GO:0016814 | Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines | IEA | molecular_function |
| GO:0045087 | Innate immune response | IEA | biological_process |
| GO:0047844 | Deoxycytidine deaminase activity | IMP | molecular_function |
| GO:0051607 | Defense response to virus | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7222165609 | 0.0000064625 | 0.9999902473 | 0.0069833333 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -2.5689838803 |
| GSE13712_SHEAR | Up | 0.1328352714 |
| GSE13712_STATIC | Down | -0.4026500578 |
| GSE19018 | Up | 0.5191049672 |
| GSE19899_A1 | Down | -4.0110854131 |
| GSE19899_A2 | Down | -3.8191868508 |
| PubMed_21979375_A1 | Down | -4.6032034946 |
| PubMed_21979375_A2 | Down | -7.4766655067 |
| GSE35957 | Down | -4.2558969897 |
| GSE36640 | Down | -6.0751428259 |
| GSE54402 | Down | -1.4092874476 |
| GSE9593 | Down | -0.6156468355 |
| GSE43922 | Down | -3.8105755385 |
| GSE24585 | Up | 1.7082907558 |
| GSE37065 | Down | -0.4226737913 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -1.3479373681 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016537 | Microarray | Functional MTI (Weak) | 20304954 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
