HCSGD entry for PREPL
1. General information
| Official gene symbol | PREPL |
|---|---|
| Entrez ID | 9581 |
| Gene full name | prolyl endopeptidase-like |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004252 | Serine-type endopeptidase activity | IEA | molecular_function |
| GO:0005829 | Cytosol | IEA | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0070008 | Serine-type exopeptidase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0740951142 | 0.4650815850 | 0.5781856550 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4576891403 |
| GSE13712_SHEAR | Down | -0.1536024265 |
| GSE13712_STATIC | Down | -0.2081998729 |
| GSE19018 | Up | 0.4665848682 |
| GSE19899_A1 | Up | 0.0031721363 |
| GSE19899_A2 | Up | 0.3158370648 |
| PubMed_21979375_A1 | Down | -0.0580517854 |
| PubMed_21979375_A2 | Down | -0.0012633891 |
| GSE35957 | Up | 0.8419307537 |
| GSE36640 | Up | 1.0761295446 |
| GSE54402 | Down | -0.3612575038 |
| GSE9593 | Up | 0.4379636820 |
| GSE43922 | Down | -0.0180844118 |
| GSE24585 | Down | -0.0441469388 |
| GSE37065 | Down | -0.1290582610 |
| GSE28863_A1 | Down | -0.0390239821 |
| GSE28863_A2 | Up | 0.2143041419 |
| GSE28863_A3 | Down | -0.6625054856 |
| GSE28863_A4 | Down | -0.3701209341 |
| GSE48662 | Up | 0.8728914526 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-21-5p | MIMAT0000076 | MIRT030991 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-125a-5p | MIMAT0000443 | MIRT045698 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
