HCSGD entry for CIR1

1. General information

Official gene symbolCIR1
Entrez ID9541
Gene full namecorepressor interacting with RBPJ, 1
Other gene symbolsCIR
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000118Histone deacetylase complexIDAcellular_component
GO:0003700Sequence-specific DNA binding transcription factor activityTASmolecular_function
GO:0003705RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activityTASmolecular_function
GO:0003714Transcription corepressor activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0005815Microtubule organizing centerIEAcellular_component
GO:0006357Regulation of transcription from RNA polymerase II promoterTASbiological_process
GO:0006366Transcription from RNA polymerase II promoterTASbiological_process
GO:0006397MRNA processingIEAbiological_process
GO:0008380RNA splicingIEAbiological_process
GO:0016607Nuclear speckIEAcellular_component
GO:0045892Negative regulation of transcription, DNA-templatedIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.71217666500.29231001100.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1354852318
GSE13712_SHEARDown-0.0977532557
GSE13712_STATICUp0.0795108525
GSE19018Up0.5013971022
GSE19899_A1Down-0.0088124530
GSE19899_A2Down-0.2808825316
PubMed_21979375_A1Down-0.6010751861
PubMed_21979375_A2Down-0.7809605602
GSE35957Up0.1170395931
GSE36640Up0.1043605229
GSE54402Down-0.1291860641
GSE9593Down-0.1951411384
GSE43922Down-0.0526320208
GSE24585Up0.2903091335
GSE37065Up0.2478008423
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.3268042716

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.