HCSGD entry for BAG4

1. General information

Official gene symbolBAG4
Entrez ID9530
Gene full nameBCL2-associated athanogene 4
Other gene symbolsBAG-4 SODD
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005057Receptor signaling protein activityTASmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolIDAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0006457Protein foldingTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0010763Positive regulation of fibroblast migrationIEAbiological_process
GO:0030838Positive regulation of actin filament polymerizationIEAbiological_process
GO:0033138Positive regulation of peptidyl-serine phosphorylationIEAbiological_process
GO:0035556Intracellular signal transductionTASbiological_process
GO:0043066Negative regulation of apoptotic processTASbiological_process
GO:0045785Positive regulation of cell adhesionIEAbiological_process
GO:0051087Chaperone bindingIEAmolecular_function
GO:0051291Protein heterooligomerizationIEAbiological_process
GO:0051496Positive regulation of stress fiber assemblyIEAbiological_process
GO:0051897Positive regulation of protein kinase B signalingIEAbiological_process
GO:0071356Cellular response to tumor necrosis factorIDAbiological_process
GO:0071364Cellular response to epidermal growth factor stimulusIEAbiological_process
GO:0072659Protein localization to plasma membraneIEAbiological_process
GO:0090367Negative regulation of mRNA modificationIEAbiological_process
GO:0097178Ruffle assemblyIEAbiological_process
GO:2001145Negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activityIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.23468778160.62957867480.91763380371.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0282339737
GSE13712_SHEARUp0.4073152351
GSE13712_STATICUp0.2117820614
GSE19018Up0.2006180403
GSE19899_A1Up0.0478533879
GSE19899_A2Down-0.0614734330
PubMed_21979375_A1Up0.8912712521
PubMed_21979375_A2Up0.3545642822
GSE35957Up0.1787669637
GSE36640Up0.2572267138
GSE54402Up0.0172558804
GSE9593Up0.1091260587
GSE43922Down-0.0298838116
GSE24585Up0.3693253947
GSE37065Down-0.0051516751
GSE28863_A1Down-0.3328245284
GSE28863_A2Up0.0175106176
GSE28863_A3Down-0.8062850254
GSE28863_A4Down-0.1868431252
GSE48662Up0.0426054132

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-96-5pMIMAT0000095MIRT027895SequencingFunctional MTI (Weak)20371350
hsa-miR-183-5pMIMAT0000261MIRT047049CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.