HCSGD entry for BAG5
1. General information
| Official gene symbol | BAG5 |
|---|---|
| Entrez ID | 9529 |
| Gene full name | BCL2-associated athanogene 5 |
| Other gene symbols | BAG-5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0006457 | Protein folding | TAS | biological_process |
| GO:0016234 | Inclusion body | IDA | cellular_component |
| GO:0031397 | Negative regulation of protein ubiquitination | ISS | biological_process |
| GO:0031625 | Ubiquitin protein ligase binding | IEA ISS | molecular_function |
| GO:0048471 | Perinuclear region of cytoplasm | IDA | cellular_component |
| GO:0051087 | Chaperone binding | IEA IPI | molecular_function |
| GO:0051444 | Negative regulation of ubiquitin-protein ligase activity | IEA ISS | biological_process |
| GO:0061084 | Negative regulation of protein refolding | IEA ISS | biological_process |
| GO:0070997 | Neuron death | IEA ISS | biological_process |
| GO:0090083 | Regulation of inclusion body assembly | IEA IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1683488583 | 0.9257804719 | 0.8090845060 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0270324149 |
| GSE13712_SHEAR | Up | 0.1828049001 |
| GSE13712_STATIC | Up | 0.1178395838 |
| GSE19018 | Down | -0.1456760311 |
| GSE19899_A1 | Down | -0.0973322615 |
| GSE19899_A2 | Up | 0.2605685239 |
| PubMed_21979375_A1 | Up | 1.0457156371 |
| PubMed_21979375_A2 | Up | 0.3152433627 |
| GSE35957 | Up | 0.1447765955 |
| GSE36640 | Up | 0.0116861840 |
| GSE54402 | Up | 0.2158438824 |
| GSE9593 | Down | -0.0756334744 |
| GSE43922 | Up | 0.2367277667 |
| GSE24585 | Down | -0.2311446994 |
| GSE37065 | Up | 0.0406661472 |
| GSE28863_A1 | Up | 0.4001410547 |
| GSE28863_A2 | Up | 0.2183945078 |
| GSE28863_A3 | Down | -0.0293255698 |
| GSE28863_A4 | Up | 0.0306381573 |
| GSE48662 | Up | 0.0830981518 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020553 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022122 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-1 | MIMAT0000416 | MIRT023533 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032220 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040079 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041624 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
