HCSGD entry for TMEM59
1. General information
| Official gene symbol | TMEM59 |
|---|---|
| Entrez ID | 9528 |
| Gene full name | transmembrane protein 59 |
| Other gene symbols | C1orf8 HSPC001 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | IEA | cellular_component |
| GO:0004175 | Endopeptidase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005764 | Lysosome | IDA | cellular_component |
| GO:0005765 | Lysosomal membrane | IEA | cellular_component |
| GO:0005770 | Late endosome | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0006914 | Autophagy | IEA | biological_process |
| GO:0010508 | Positive regulation of autophagy | IMP | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0031902 | Late endosome membrane | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0786109152 | 0.8739815774 | 0.5909999715 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1601936827 |
| GSE13712_SHEAR | Down | -0.0584087097 |
| GSE13712_STATIC | Down | -0.0109189124 |
| GSE19018 | Up | 0.5949374865 |
| GSE19899_A1 | Up | 0.1718016482 |
| GSE19899_A2 | Down | -0.0485900650 |
| PubMed_21979375_A1 | Up | 0.3294633092 |
| PubMed_21979375_A2 | Up | 0.1081933918 |
| GSE35957 | Down | -0.0915468160 |
| GSE36640 | Up | 0.7135363715 |
| GSE54402 | Down | -0.1763169906 |
| GSE9593 | Up | 0.0597484024 |
| GSE43922 | Up | 0.1676432202 |
| GSE24585 | Up | 0.6197207129 |
| GSE37065 | Up | 0.2219823066 |
| GSE28863_A1 | Up | 0.0050537550 |
| GSE28863_A2 | Up | 0.2216636142 |
| GSE28863_A3 | Down | -0.5149244165 |
| GSE28863_A4 | Down | -0.2062373771 |
| GSE48662 | Up | 0.1949222752 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30a-5p | MIMAT0000087 | MIRT005138 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045645 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-1260b | MIMAT0015041 | MIRT052744 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
