HCSGD entry for NPEPPS
1. General information
| Official gene symbol | NPEPPS |
|---|---|
| Entrez ID | 9520 |
| Gene full name | aminopeptidase puromycin sensitive |
| Other gene symbols | AAP-S MP100 PSA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000209 | Protein polyubiquitination | TAS | biological_process |
| GO:0002474 | Antigen processing and presentation of peptide antigen via MHC class I | TAS | biological_process |
| GO:0004177 | Aminopeptidase activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0008237 | Metallopeptidase activity | IEA | molecular_function |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0071456 | Cellular response to hypoxia | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0392398389 | 0.9787998100 | 0.4465334198 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0364869492 |
| GSE13712_SHEAR | Up | 0.1786829989 |
| GSE13712_STATIC | Up | 0.1680313450 |
| GSE19018 | Up | 0.5185217578 |
| GSE19899_A1 | Up | 0.4307636688 |
| GSE19899_A2 | Up | 0.1673630532 |
| PubMed_21979375_A1 | Down | -0.0615734107 |
| PubMed_21979375_A2 | Up | 0.8656150127 |
| GSE35957 | Down | -0.1455726300 |
| GSE36640 | Up | 0.1281786748 |
| GSE54402 | Up | 0.1317773447 |
| GSE9593 | Up | 0.5234678260 |
| GSE43922 | Up | 0.1671545122 |
| GSE24585 | Up | 0.4848638545 |
| GSE37065 | Down | -0.0684907443 |
| GSE28863_A1 | Up | 0.1827504063 |
| GSE28863_A2 | Up | 0.2061251906 |
| GSE28863_A3 | Down | -0.1024275974 |
| GSE28863_A4 | Up | 0.0150281107 |
| GSE48662 | Down | -0.0156708891 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| CHR-2797 | DB05745 | - |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-122-5p | MIMAT0000421 | MIRT023333 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-484 | MIMAT0002174 | MIRT041818 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-3p | MIMAT0001340 | MIRT042580 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044392 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-27b-3p | MIMAT0000419 | MIRT046171 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT048787 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
