HCSGD entry for LITAF
1. General information
| Official gene symbol | LITAF |
|---|---|
| Entrez ID | 9516 |
| Gene full name | lipopolysaccharide-induced TNF factor |
| Other gene symbols | PIG7 SIMPLE TP53I7 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001817 | Regulation of cytokine production | IEA | biological_process |
| GO:0004871 | Signal transducer activity | IMP | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005765 | Lysosomal membrane | IDA | cellular_component |
| GO:0005794 | Golgi apparatus | IDA IMP | cellular_component |
| GO:0005886 | Plasma membrane | IMP | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0007165 | Signal transduction | IMP | biological_process |
| GO:0007568 | Aging | IEA | biological_process |
| GO:0042347 | Negative regulation of NF-kappaB import into nucleus | IEA | biological_process |
| GO:0043123 | Positive regulation of I-kappaB kinase/NF-kappaB signaling | IMP | biological_process |
| GO:0050699 | WW domain binding | IPI | molecular_function |
| GO:0071222 | Cellular response to lipopolysaccharide | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7181101212 | 0.0170616390 | 0.9999902473 | 0.2558856980 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2663003098 |
| GSE13712_SHEAR | Down | -1.7116648561 |
| GSE13712_STATIC | Down | -1.8072702591 |
| GSE19018 | Down | -0.1542971838 |
| GSE19899_A1 | Down | -0.5648390968 |
| GSE19899_A2 | Down | -0.2354039018 |
| PubMed_21979375_A1 | Down | -0.2420146509 |
| PubMed_21979375_A2 | Down | -0.1725727137 |
| GSE35957 | Down | -0.0753284228 |
| GSE36640 | Down | -1.0183784293 |
| GSE54402 | Down | -0.6573476290 |
| GSE9593 | Up | 0.1136705850 |
| GSE43922 | Down | -0.4021860919 |
| GSE24585 | Up | 0.1426014066 |
| GSE37065 | Down | -0.0881539358 |
| GSE28863_A1 | Up | 0.1631870736 |
| GSE28863_A2 | Up | 0.3385814012 |
| GSE28863_A3 | Up | 0.1767725132 |
| GSE28863_A4 | Up | 0.2331143609 |
| GSE48662 | Up | 0.4440549904 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT002728 | Microarray | Functional MTI (Weak) | 15685193 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT002728 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-375 | MIMAT0000728 | MIRT019921 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-128-3p | MIMAT0000424 | MIRT022102 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-128-3p | MIMAT0000424 | MIRT022102 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025880 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025880 | Microarray | Functional MTI (Weak) | 19073608 |
| hsa-miR-27a-3p | MIMAT0000084 | MIRT028706 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-320a | MIMAT0000510 | MIRT044539 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
