HCSGD entry for PMPCB


1. General information

Official gene symbolPMPCB
Entrez ID9512
Gene full namepeptidase (mitochondrial processing) beta
Other gene symbolsBeta-MPP MPP11 MPPB MPPP52 P-52
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003824Catalytic activityIEAmolecular_function
GO:0004222Metalloendopeptidase activityIEAmolecular_function
GO:0005743Mitochondrial inner membraneIEAcellular_component
GO:0005759Mitochondrial matrixIEAcellular_component
GO:0006508ProteolysisIEAbiological_process
GO:0006626Protein targeting to mitochondrionTASbiological_process
GO:0044267Cellular protein metabolic processTASbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.50589001180.29782144680.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1861231887
GSE13712_SHEARDown-0.0733846099
GSE13712_STATICUp0.0917588114
GSE19018Down-0.2648547296
GSE19899_A1Down-0.0284976285
GSE19899_A2Up0.0194235090
PubMed_21979375_A1Up0.1100586249
PubMed_21979375_A2Down-0.0747668555
GSE35957Down-0.0574643404
GSE36640Down-0.2550501271
GSE54402Down-0.0138361224
GSE9593Down-0.0488521418
GSE43922Down-0.1593973758
GSE24585Up0.0399989824
GSE37065Down-0.1243824635
GSE28863_A1Up0.9279518115
GSE28863_A2Up0.9452267129
GSE28863_A3Up0.0033312643
GSE28863_A4Down-0.3246370359
GSE48662Up0.1733567110

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.