HCSGD entry for ADAMTS2
1. General information
| Official gene symbol | ADAMTS2 |
|---|---|
| Entrez ID | 9509 |
| Gene full name | ADAM metallopeptidase with thrombospondin type 1 motif, 2 |
| Other gene symbols | ADAM-TS2 ADAMTS-2 ADAMTS-3 NPI PC I-NP PCI-NP PCINP PCPNI PNPI |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004222 | Metalloendopeptidase activity | IEA | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005578 | Proteinaceous extracellular matrix | IEA | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0007283 | Spermatogenesis | IEA | biological_process |
| GO:0008237 | Metallopeptidase activity | TAS | molecular_function |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016485 | Protein processing | IEA | biological_process |
| GO:0030198 | Extracellular matrix organization | TAS | biological_process |
| GO:0030199 | Collagen fibril organization | IEA | biological_process |
| GO:0030324 | Lung development | IEA | biological_process |
| GO:0030574 | Collagen catabolic process | IEA | biological_process |
| GO:0043588 | Skin development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8088219141 | 0.0028954181 | 0.9999902473 | 0.1074195499 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.9267244625 |
| GSE13712_SHEAR | Up | 0.1150757043 |
| GSE13712_STATIC | Down | -0.0847813388 |
| GSE19018 | Up | 0.0937918321 |
| GSE19899_A1 | Down | -0.6793449489 |
| GSE19899_A2 | Down | -1.2123958237 |
| PubMed_21979375_A1 | Down | -1.3498016864 |
| PubMed_21979375_A2 | Down | -1.1654673260 |
| GSE35957 | Down | -0.1817477670 |
| GSE36640 | Down | -0.6395299278 |
| GSE54402 | Down | -1.0292323902 |
| GSE9593 | Up | 0.1272998655 |
| GSE43922 | Down | -1.3179807092 |
| GSE24585 | Down | -0.0667284617 |
| GSE37065 | Down | -0.6238121394 |
| GSE28863_A1 | Up | 1.2512938105 |
| GSE28863_A2 | Up | 0.4926273800 |
| GSE28863_A3 | Up | 0.0678251560 |
| GSE28863_A4 | Down | -0.4280884354 |
| GSE48662 | Up | 0.3226134302 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-106b-3p | MIMAT0004672 | MIRT038560 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
