HCSGD entry for SLC4A7
1. General information
| Official gene symbol | SLC4A7 |
|---|---|
| Entrez ID | 9497 |
| Gene full name | solute carrier family 4, sodium bicarbonate cotransporter, member 7 |
| Other gene symbols | NBC2 NBC3 NBCN1 SBC2 SLC4A6 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005452 | Inorganic anion exchanger activity | IEA | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006811 | Ion transport | TAS | biological_process |
| GO:0008510 | Sodium:bicarbonate symporter activity | NAS | molecular_function |
| GO:0015698 | Inorganic anion transport | NAS | biological_process |
| GO:0015701 | Bicarbonate transport | NAS TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA NAS | cellular_component |
| GO:0016323 | Basolateral plasma membrane | IEA | cellular_component |
| GO:0016324 | Apical plasma membrane | IEA | cellular_component |
| GO:0021747 | Cochlear nucleus development | IEA | biological_process |
| GO:0032420 | Stereocilium | IEA | cellular_component |
| GO:0034220 | Ion transmembrane transport | NAS | biological_process |
| GO:0035725 | Sodium ion transmembrane transport | NAS | biological_process |
| GO:0046666 | Retinal cell programmed cell death | IEA | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
| GO:0060117 | Auditory receptor cell development | IEA | biological_process |
| GO:0061299 | Retina vasculature morphogenesis in camera-type eye | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0044247255 | 0.7932131454 | 0.1773174242 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1974080111 |
| GSE13712_SHEAR | Up | 0.0984516687 |
| GSE13712_STATIC | Down | -0.0194190834 |
| GSE19018 | Up | 0.3299166458 |
| GSE19899_A1 | Up | 1.2744231966 |
| GSE19899_A2 | Up | 0.6174343056 |
| PubMed_21979375_A1 | Up | 1.2017821391 |
| PubMed_21979375_A2 | Up | 1.1134790819 |
| GSE35957 | Up | 1.4039669958 |
| GSE36640 | Down | -0.0443197778 |
| GSE54402 | Up | 1.1385414332 |
| GSE9593 | Up | 0.5263331692 |
| GSE43922 | Up | 0.7917970225 |
| GSE24585 | Down | -0.4287331859 |
| GSE37065 | Down | -0.1433285356 |
| GSE28863_A1 | Up | 0.0249819756 |
| GSE28863_A2 | Up | 0.1354093043 |
| GSE28863_A3 | Down | -0.7326421084 |
| GSE28863_A4 | Down | -0.1800036648 |
| GSE48662 | Down | -0.0119844237 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30a-5p | MIMAT0000087 | MIRT005132 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025465 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031193 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-25-3p | MIMAT0000081 | MIRT050222 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
