HCSGD entry for PIGB
1. General information
| Official gene symbol | PIGB |
|---|---|
| Entrez ID | 9488 |
| Gene full name | phosphatidylinositol glycan anchor biosynthesis, class B |
| Other gene symbols | GPI-MT-III PIG-B |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000030 | Mannosyltransferase activity | IDA | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | IDA IEA TAS | cellular_component |
| GO:0006501 | C-terminal protein lipidation | TAS | biological_process |
| GO:0006506 | GPI anchor biosynthetic process | IDA | biological_process |
| GO:0016021 | Integral component of membrane | NAS | cellular_component |
| GO:0016254 | Preassembly of GPI anchor in ER membrane | TAS | biological_process |
| GO:0016757 | Transferase activity, transferring glycosyl groups | IEA | molecular_function |
| GO:0043687 | Post-translational protein modification | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0097502 | Mannosylation | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4452974621 | 0.0950223320 | 0.9999902473 | 0.5875223867 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0658108260 |
| GSE13712_SHEAR | Down | -0.0564592227 |
| GSE13712_STATIC | Up | 0.4669963647 |
| GSE19018 | Up | 0.4164203517 |
| GSE19899_A1 | Down | -0.4596732594 |
| GSE19899_A2 | Down | -0.3135961189 |
| PubMed_21979375_A1 | Down | -0.0151606262 |
| PubMed_21979375_A2 | Down | -0.2081080650 |
| GSE35957 | Up | 0.2648430196 |
| GSE36640 | Up | 0.9197918295 |
| GSE54402 | Down | -0.4311725998 |
| GSE9593 | Up | 0.1616589811 |
| GSE43922 | Down | -0.3057975535 |
| GSE24585 | Up | 0.2930189860 |
| GSE37065 | Up | 0.3416377112 |
| GSE28863_A1 | Down | -0.3216084046 |
| GSE28863_A2 | Down | -0.2953355172 |
| GSE28863_A3 | Down | -0.6019074185 |
| GSE28863_A4 | Up | 0.1307399102 |
| GSE48662 | Down | -0.4655057763 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019704 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-9-5p | MIMAT0000441 | MIRT021352 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045396 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
