HCSGD entry for PCYT1B
1. General information
| Official gene symbol | PCYT1B |
|---|---|
| Entrez ID | 9468 |
| Gene full name | phosphate cytidylyltransferase 1, choline, beta |
| Other gene symbols | CCTB CTB |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001541 | Ovarian follicle development | IEA | biological_process |
| GO:0003824 | Catalytic activity | IEA | molecular_function |
| GO:0004105 | Choline-phosphate cytidylyltransferase activity | IEA | molecular_function |
| GO:0005737 | Cytoplasm | TAS | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006644 | Phospholipid metabolic process | TAS | biological_process |
| GO:0006656 | Phosphatidylcholine biosynthetic process | TAS | biological_process |
| GO:0006657 | CDP-choline pathway | TAS | biological_process |
| GO:0007283 | Spermatogenesis | IEA | biological_process |
| GO:0009058 | Biosynthetic process | IEA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046474 | Glycerophospholipid biosynthetic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8704113636 | 0.6796569241 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0193836318 |
| GSE13712_SHEAR | Up | 0.1353743620 |
| GSE13712_STATIC | Down | -0.2169527611 |
| GSE19018 | Up | 0.0248804143 |
| GSE19899_A1 | Up | 0.0148881549 |
| GSE19899_A2 | Down | -0.0008939849 |
| PubMed_21979375_A1 | Down | -0.0469051349 |
| PubMed_21979375_A2 | Down | -0.0141806448 |
| GSE35957 | Up | 0.0798530157 |
| GSE36640 | Up | 0.0334662958 |
| GSE54402 | Down | -0.1459757702 |
| GSE9593 | Down | -0.0087217865 |
| GSE43922 | Up | 0.0159242653 |
| GSE24585 | Down | -0.0304288381 |
| GSE37065 | Up | 0.1633058938 |
| GSE28863_A1 | Down | -0.0570530149 |
| GSE28863_A2 | Down | -0.1607676388 |
| GSE28863_A3 | Up | 0.3037977341 |
| GSE28863_A4 | Down | -0.0463369586 |
| GSE48662 | Up | 0.0172581483 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Choline | DB00122 | NUTR00020 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7b-5p | MIMAT0000063 | MIRT032240 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
