HCSGD entry for AKAP7
1. General information
| Official gene symbol | AKAP7 |
|---|---|
| Entrez ID | 9465 |
| Gene full name | A kinase (PRKA) anchor protein 7 |
| Other gene symbols | AKAP15 AKAP18 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0001508 | Action potential | IC | biological_process |
| GO:0003824 | Catalytic activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006811 | Ion transport | TAS | biological_process |
| GO:0008104 | Protein localization | IC | biological_process |
| GO:0008150 | Biological_process | ND | biological_process |
| GO:0016324 | Apical plasma membrane | IDA | cellular_component |
| GO:0016328 | Lateral plasma membrane | IDA | cellular_component |
| GO:0019901 | Protein kinase binding | IEA | molecular_function |
| GO:0034237 | Protein kinase A regulatory subunit binding | IEA | molecular_function |
| GO:0035556 | Intracellular signal transduction | TAS | biological_process |
| GO:0051018 | Protein kinase A binding | IDA TAS | molecular_function |
| GO:0060306 | Regulation of membrane repolarization | IDA | biological_process |
| GO:0071320 | Cellular response to cAMP | IDA | biological_process |
| GO:1901381 | Positive regulation of potassium ion transmembrane transport | IDA | biological_process |
| GO:1902261 | Positive regulation of delayed rectifier potassium channel activity | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9965409293 | 0.0158303826 | 0.9999902473 | 0.2460568477 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3984455565 |
| GSE13712_SHEAR | Down | -0.2274019142 |
| GSE13712_STATIC | Down | -0.1805000967 |
| GSE19018 | Down | -0.1711847346 |
| GSE19899_A1 | Down | -0.2354530985 |
| GSE19899_A2 | Down | -0.8317201453 |
| PubMed_21979375_A1 | Down | -0.3089296275 |
| PubMed_21979375_A2 | Down | -0.9702172208 |
| GSE35957 | Down | -0.0301675545 |
| GSE36640 | Down | -0.5533767044 |
| GSE54402 | Down | -0.2666525551 |
| GSE9593 | Down | -0.1080718127 |
| GSE43922 | Down | -0.1936664019 |
| GSE24585 | Down | -0.0946968036 |
| GSE37065 | Down | -0.1459535655 |
| GSE28863_A1 | Up | 0.0093645758 |
| GSE28863_A2 | Up | 0.0157874280 |
| GSE28863_A3 | Down | -0.2650396438 |
| GSE28863_A4 | Down | -0.2768182116 |
| GSE48662 | Down | -0.0003211362 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019848 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024297 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026405 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-24-3p | MIMAT0000080 | MIRT030508 | Microarray | Functional MTI (Weak) | 19748357 |
| hsa-miR-484 | MIMAT0002174 | MIRT041881 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
