HCSGD entry for HOMER1

1. General information

Official gene symbolHOMER1
Entrez ID9456
Gene full namehomer homolog 1 (Drosophila)
Other gene symbolsHOMER HOMER1A HOMER1B HOMER1C SYN47 Ves-1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003009Skeletal muscle contractionIEAbiological_process
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0007206Phospholipase C-activating G-protein coupled glutamate receptor signaling pathwayTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007623Circadian rhythmIEAbiological_process
GO:0009967Positive regulation of signal transductionICbiological_process
GO:0030018Z discIEAcellular_component
GO:0030054Cell junctionIEAcellular_component
GO:0031802Type 5 metabotropic glutamate receptor bindingIEAmolecular_function
GO:0032947Protein complex scaffoldIEAmolecular_function
GO:0035094Response to nicotineIEAbiological_process
GO:0035418Protein localization to synapseIEAbiological_process
GO:0035591Signaling adaptor activityICmolecular_function
GO:0042802Identical protein bindingIEAmolecular_function
GO:0043025Neuronal cell bodyIEAcellular_component
GO:0043034CostamereIEAcellular_component
GO:0043198Dendritic shaftIEAcellular_component
GO:0044325Ion channel bindingIPImolecular_function
GO:0045177Apical part of cellIEAcellular_component
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0046982Protein heterodimerization activityIEAmolecular_function
GO:0048148Behavioral response to cocaineIEAbiological_process
GO:0048741Skeletal muscle fiber developmentIEAbiological_process
GO:0048875Chemical homeostasis within a tissueIEAbiological_process
GO:0051592Response to calcium ionIDAbiological_process
GO:0051928Positive regulation of calcium ion transportIEAbiological_process
GO:0090279Regulation of calcium ion importIEAbiological_process
GO:0097110Scaffold protein bindingIEAmolecular_function
GO:0097481Neuronal postsynaptic densityIEAcellular_component
GO:2001256Regulation of store-operated calcium entryTASbiological_process
GO:2001257Regulation of cation channel activityTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.13482521180.01593052700.74333895970.2461419355

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-1.3948616755
GSE13712_SHEARDown-0.1846206927
GSE13712_STATICDown-0.0406423174
GSE19018Down-0.7925279346
GSE19899_A1Up0.5846415276
GSE19899_A2Up0.1542040513
PubMed_21979375_A1Up2.1636237774
PubMed_21979375_A2Up0.8325998104
GSE35957Down-0.9621364629
GSE36640Down-0.5941265288
GSE54402Up0.9606846127
GSE9593Down-0.7365127103
GSE43922Up0.7186640650
GSE24585Down-0.1672823808
GSE37065Up0.3454595339
GSE28863_A1Down-0.3938695490
GSE28863_A2Up0.0242674221
GSE28863_A3Down-0.4725065361
GSE28863_A4Down-0.4350672287
GSE48662Down-0.4230869836

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-let-7d-5pMIMAT0000065MIRT032118SequencingFunctional MTI (Weak)20371350
hsa-miR-484MIMAT0002174MIRT042276CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.