HCSGD entry for GSTO1

1. General information

Official gene symbolGSTO1
Entrez ID9446
Gene full nameglutathione S-transferase omega 1
Other gene symbolsGSTO 1-1 GSTTLp28 P28 SPG-R
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004364Glutathione transferase activityIDA IEAmolecular_function
GO:0005737CytoplasmIDA IEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006805Xenobiotic metabolic processTASbiological_process
GO:0010880Regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulumIDAbiological_process
GO:0010881Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ionICbiological_process
GO:0014810Positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ionICbiological_process
GO:0016491Oxidoreductase activityIDAmolecular_function
GO:0019852L-ascorbic acid metabolic processIDAbiological_process
GO:0042178Xenobiotic catabolic processIDAbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045174Glutathione dehydrogenase (ascorbate) activityIDAmolecular_function
GO:0050610Methylarsonate reductase activityIEAmolecular_function
GO:0060315Negative regulation of ryanodine-sensitive calcium-release channel activityIDAbiological_process
GO:0060316Positive regulation of ryanodine-sensitive calcium-release channel activityIDAbiological_process
GO:0071243Cellular response to arsenic-containing substanceIDAbiological_process
GO:1901687Glutathione derivative biosynthetic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.01287495160.94261710800.28380875731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up1.0707976304
GSE13712_SHEARDown-0.1368504839
GSE13712_STATICDown-0.0239560554
GSE19018Up0.1132347194
GSE19899_A1Up0.4412909277
GSE19899_A2Up0.4733616137
PubMed_21979375_A1Up0.9367847782
PubMed_21979375_A2Up0.5945421064
GSE35957Down-0.2627481506
GSE36640Up0.1899313138
GSE54402Up0.6622572765
GSE9593Up0.5353124459
GSE43922Up0.4772145460
GSE24585Down-0.5692059515
GSE37065Up0.4924859673
GSE28863_A1Down-0.1051364110
GSE28863_A2Up0.0252676431
GSE28863_A3Up0.3379923509
GSE28863_A4Up0.1665640043
GSE48662Down-0.2993783464

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

GlutathioneDB00143 NUTR00029 | EXPT01650

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1MIMAT0000416MIRT023892ProteomicsFunctional MTI (Weak)18668040
hsa-miR-197-3pMIMAT0000227MIRT048048CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.