HCSGD entry for KCNK6
1. General information
| Official gene symbol | KCNK6 |
|---|---|
| Entrez ID | 9424 |
| Gene full name | potassium channel, subfamily K, member 6 |
| Other gene symbols | K2p6.1 KCNK8 TOSS TWIK-2 TWIK2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003085 | Negative regulation of systemic arterial blood pressure | IEA | biological_process |
| GO:0005242 | Inward rectifier potassium channel activity | TAS | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006813 | Potassium ion transport | TAS | biological_process |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0008076 | Voltage-gated potassium channel complex | TAS | cellular_component |
| GO:0060075 | Regulation of resting membrane potential | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9793058736 | 0.0035043805 | 0.9999902473 | 0.1202554688 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3740110062 |
| GSE13712_SHEAR | Down | -1.1174928441 |
| GSE13712_STATIC | Down | -0.5928978132 |
| GSE19018 | Down | -0.2526698956 |
| GSE19899_A1 | Down | -0.2119575603 |
| GSE19899_A2 | Down | -1.2933227257 |
| PubMed_21979375_A1 | Down | -2.7157945600 |
| PubMed_21979375_A2 | Down | -0.3329954393 |
| GSE35957 | Up | 0.2908313804 |
| GSE36640 | Up | 0.2462481971 |
| GSE54402 | Down | -1.2069128289 |
| GSE9593 | Down | -0.5439491013 |
| GSE43922 | Down | -0.0086188610 |
| GSE24585 | Up | 0.0080987199 |
| GSE37065 | Down | -0.1279635044 |
| GSE28863_A1 | Down | -0.7278446987 |
| GSE28863_A2 | Down | -0.0911520582 |
| GSE28863_A3 | Up | 0.0023560793 |
| GSE28863_A4 | Up | 0.1261532076 |
| GSE48662 | Up | 0.2264679893 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Ibutilide | DB00308 | APRD01025 |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
