HCSGD entry for GNG8
1. General information
| Official gene symbol | GNG8 |
|---|---|
| Entrez ID | 94235 |
| Gene full name | guanine nucleotide binding protein (G protein), gamma 8 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003924 | GTPase activity | NAS | molecular_function |
| GO:0004871 | Signal transducer activity | NAS | molecular_function |
| GO:0005834 | Heterotrimeric G-protein complex | IEA | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006112 | Energy reserve metabolic process | TAS | biological_process |
| GO:0006184 | GTP catabolic process | NAS | biological_process |
| GO:0007186 | G-protein coupled receptor signaling pathway | NAS | biological_process |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0007399 | Nervous system development | IEA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0071377 | Cellular response to glucagon stimulus | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0903245089 | 0.9555482315 | 0.6322955851 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2298110574 |
| GSE13712_SHEAR | Up | 0.1476273464 |
| GSE13712_STATIC | Up | 0.1170918239 |
| GSE19018 | Up | 0.4520028971 |
| GSE19899_A1 | Down | -0.0690476845 |
| GSE19899_A2 | Up | 0.1286870838 |
| PubMed_21979375_A1 | Up | 0.3046099066 |
| PubMed_21979375_A2 | Up | 0.1669518925 |
| GSE35957 | Up | 0.0234162580 |
| GSE36640 | Down | -0.0501234726 |
| GSE54402 | Up | 0.1660473447 |
| GSE9593 | Up | 0.0747622445 |
| GSE43922 | Up | 0.3172031164 |
| GSE24585 | Down | -0.0458227257 |
| GSE37065 | Down | -0.0290776198 |
| GSE28863_A1 | Down | -0.0402363176 |
| GSE28863_A2 | Up | 0.0486854788 |
| GSE28863_A3 | Up | 0.1438114142 |
| GSE28863_A4 | Up | 0.2983199368 |
| GSE48662 | Up | 0.1683478573 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017556 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
