HCSGD entry for NTN1
1. General information
| Official gene symbol | NTN1 |
|---|---|
| Entrez ID | 9423 |
| Gene full name | netrin 1 |
| Other gene symbols | NTN1L |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001764 | Neuron migration | IEA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005604 | Basement membrane | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0007411 | Axon guidance | TAS | biological_process |
| GO:0008284 | Positive regulation of cell proliferation | IEA | biological_process |
| GO:0016337 | Cell-cell adhesion | IEA | biological_process |
| GO:0030334 | Regulation of cell migration | IEA | biological_process |
| GO:0030517 | Negative regulation of axon extension | IEA | biological_process |
| GO:0033564 | Anterior/posterior axon guidance | IEA | biological_process |
| GO:0040023 | Establishment of nucleus localization | IEA | biological_process |
| GO:0042472 | Inner ear morphogenesis | IEA | biological_process |
| GO:0045773 | Positive regulation of axon extension | IEA | biological_process |
| GO:0060603 | Mammary gland duct morphogenesis | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0418184757 | 0.9352800122 | 0.4574625311 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0354006813 |
| GSE13712_SHEAR | Down | -0.0250335506 |
| GSE13712_STATIC | Down | -0.0838326667 |
| GSE19018 | Up | 0.0374915881 |
| GSE19899_A1 | Up | 0.0564871688 |
| GSE19899_A2 | Up | 0.1400944086 |
| PubMed_21979375_A1 | Up | 0.0448602220 |
| PubMed_21979375_A2 | Down | -0.0788230672 |
| GSE35957 | Up | 0.0333546654 |
| GSE36640 | Up | 0.0049980457 |
| GSE54402 | Down | -0.0139367432 |
| GSE9593 | Down | -0.0351647069 |
| GSE43922 | Up | 0.0970442891 |
| GSE24585 | Down | -0.1201273599 |
| GSE37065 | Up | 0.3474668874 |
| GSE28863_A1 | Up | 1.7647491612 |
| GSE28863_A2 | Up | 1.2415701916 |
| GSE28863_A3 | Up | 0.5215441643 |
| GSE28863_A4 | Up | 0.1357650071 |
| GSE48662 | Down | -0.0753920075 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-148b-3p | MIMAT0000759 | MIRT019443 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-1296-5p | MIMAT0005794 | MIRT036113 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-3p | MIMAT0001340 | MIRT042477 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
