HCSGD entry for TJP2
1. General information
| Official gene symbol | TJP2 |
|---|---|
| Entrez ID | 9414 |
| Gene full name | tight junction protein 2 |
| Other gene symbols | C9DUPq21.11 DFNA51 DUP9q21.11 X104 ZO2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004385 | Guanylate kinase activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IDA IEA TAS | cellular_component |
| GO:0005912 | Adherens junction | IEA | cellular_component |
| GO:0005923 | Tight junction | IDA IEA | cellular_component |
| GO:0006915 | Apoptotic process | TAS | biological_process |
| GO:0006921 | Cellular component disassembly involved in execution phase of apoptosis | TAS | biological_process |
| GO:0008022 | Protein C-terminus binding | IEA | molecular_function |
| GO:0008152 | Metabolic process | TAS | biological_process |
| GO:0010033 | Response to organic substance | IEA | biological_process |
| GO:0016310 | Phosphorylation | TAS | biological_process |
| GO:0030054 | Cell junction | IDA | cellular_component |
| GO:0035329 | Hippo signaling | TAS | biological_process |
| GO:0046939 | Nucleotide phosphorylation | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6856158201 | 0.2563114585 | 0.9999902473 | 0.9709806995 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2093907448 |
| GSE13712_SHEAR | Up | 0.2690680144 |
| GSE13712_STATIC | Up | 0.1219500747 |
| GSE19018 | Down | -0.3516416120 |
| GSE19899_A1 | Down | -0.2346979301 |
| GSE19899_A2 | Down | -0.1412393443 |
| PubMed_21979375_A1 | Down | -0.3208748828 |
| PubMed_21979375_A2 | Down | -0.1563298026 |
| GSE35957 | Down | -0.3267146455 |
| GSE36640 | Down | -0.1771123994 |
| GSE54402 | Up | 0.1416464984 |
| GSE9593 | Down | -0.1294247621 |
| GSE43922 | Down | -0.3126005040 |
| GSE24585 | Up | 0.3324761912 |
| GSE37065 | Down | -0.1846339441 |
| GSE28863_A1 | Up | 0.1580279884 |
| GSE28863_A2 | Up | 0.2787130848 |
| GSE28863_A3 | Down | -0.2116261254 |
| GSE28863_A4 | Up | 0.1916580202 |
| GSE48662 | Down | -0.2850521136 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT002718 | Microarray | Functional MTI (Weak) | 15685193 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT002718 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-203a | MIMAT0000264 | MIRT006684 | qRT-PCR//Western blot | Functional MTI | 22101077 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016495 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024740 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025356 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026686 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
