HCSGD entry for ARHGAP29
1. General information
| Official gene symbol | ARHGAP29 |
|---|---|
| Entrez ID | 9411 |
| Gene full name | Rho GTPase activating protein 29 |
| Other gene symbols | PARG1 RP11-255E17.1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005100 | Rho GTPase activator activity | TAS | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0007264 | Small GTPase mediated signal transduction | TAS | biological_process |
| GO:0007266 | Rho protein signal transduction | TAS | biological_process |
| GO:0030165 | PDZ domain binding | IDA | molecular_function |
| GO:0032320 | Positive regulation of Ras GTPase activity | TAS | biological_process |
| GO:0032321 | Positive regulation of Rho GTPase activity | TAS | biological_process |
| GO:0035556 | Intracellular signal transduction | IEA | biological_process |
| GO:0043085 | Positive regulation of catalytic activity | TAS | biological_process |
| GO:0043547 | Positive regulation of GTPase activity | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0050790 | Regulation of catalytic activity | TAS | biological_process |
| GO:0051056 | Regulation of small GTPase mediated signal transduction | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0018225827 | 0.9774559135 | 0.1131419811 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3390641415 |
| GSE13712_SHEAR | Up | 0.3376461625 |
| GSE13712_STATIC | Up | 0.4558126938 |
| GSE19018 | Up | 0.7674119220 |
| GSE19899_A1 | Up | 0.3905572776 |
| GSE19899_A2 | Up | 0.7210343073 |
| PubMed_21979375_A1 | Up | 0.7538387566 |
| PubMed_21979375_A2 | Up | 0.7840654443 |
| GSE35957 | Up | 0.4834501704 |
| GSE36640 | Up | 0.1409309561 |
| GSE54402 | Down | -0.7499175424 |
| GSE9593 | Up | 0.8852997048 |
| GSE43922 | Up | 0.2718052688 |
| GSE24585 | Up | 0.3264746548 |
| GSE37065 | Up | 0.1563396602 |
| GSE28863_A1 | Up | 0.4982005201 |
| GSE28863_A2 | Up | 1.4804160381 |
| GSE28863_A3 | Down | -0.1750387306 |
| GSE28863_A4 | Down | -0.0611026821 |
| GSE48662 | Down | -0.1592038656 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT003762 | Microarray | Functional MTI (Weak) | 15685193 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT004075 | Microarray | Functional MTI (Weak) | 15685193 |
| hsa-miR-204-5p | MIMAT0000265 | MIRT005817 | Microarray | Functional MTI (Weak) | 21282569 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024335 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026359 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | NA | hsa-miR-1 | 15685193 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
