HCSGD entry for PAXBP1
1. General information
| Official gene symbol | PAXBP1 |
|---|---|
| Entrez ID | 94104 |
| Gene full name | PAX3 and PAX7 binding protein 1 |
| Other gene symbols | BM020 C21orf66 FSAP105 GCFC GCFC1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0007517 | Muscle organ development | IEA | biological_process |
| GO:0008134 | Transcription factor binding | IEA | molecular_function |
| GO:0014842 | Regulation of satellite cell proliferation | IEA | biological_process |
| GO:0031062 | Positive regulation of histone methylation | IEA | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:2000288 | Positive regulation of myoblast proliferation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7296152198 | 0.2306942137 | 0.9999902473 | 0.9247795309 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0258334737 |
| GSE13712_SHEAR | Down | -0.1028070005 |
| GSE13712_STATIC | Down | -0.1189125343 |
| GSE19018 | Down | -0.1270468814 |
| GSE19899_A1 | Up | 0.0951665507 |
| GSE19899_A2 | Down | -0.5655111213 |
| PubMed_21979375_A1 | Down | -0.1688379855 |
| PubMed_21979375_A2 | Up | 0.0015386961 |
| GSE35957 | Down | -0.5858682376 |
| GSE36640 | Down | -0.9111353484 |
| GSE54402 | Up | 0.3082859617 |
| GSE9593 | Down | -0.4983503404 |
| GSE43922 | Up | 0.0826998475 |
| GSE24585 | Down | -0.0911985394 |
| GSE37065 | Up | 0.0618582637 |
| GSE28863_A1 | Up | 0.3038972759 |
| GSE28863_A2 | Up | 0.4492690682 |
| GSE28863_A3 | Down | -0.3000885244 |
| GSE28863_A4 | Up | 0.1383285325 |
| GSE48662 | Down | -0.0632411836 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020708 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1 | MIMAT0000416 | MIRT023646 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-421 | MIMAT0003339 | MIRT039357 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-196b-5p | MIMAT0001080 | MIRT042661 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-27b-3p | MIMAT0000419 | MIRT046206 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7d-5p | MIMAT0000065 | MIRT051720 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052489 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
