HCSGD entry for CD80

1. General information

Official gene symbolCD80
Entrez ID941
Gene full nameCD80 molecule
Other gene symbolsB7 B7-1 B7.1 BB1 CD28LG CD28LG1 LAB7
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0007173Epidermal growth factor receptor signaling pathwayTASbiological_process
GO:0007267Cell-cell signalingICbiological_process
GO:0008543Fibroblast growth factor receptor signaling pathwayTASbiological_process
GO:0009897External side of plasma membraneIEAcellular_component
GO:0009967Positive regulation of signal transductionNASbiological_process
GO:0015026Coreceptor activityNASmolecular_function
GO:0016021Integral component of membraneICcellular_component
GO:0016032Viral processIEAbiological_process
GO:0031295T cell costimulationTASbiological_process
GO:0035556Intracellular signal transductionNASbiological_process
GO:0038095Fc-epsilon receptor signaling pathwayTASbiological_process
GO:0042110T cell activationICbiological_process
GO:0045086Positive regulation of interleukin-2 biosynthetic processNASbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0045425Positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic processNASbiological_process
GO:0045627Positive regulation of T-helper 1 cell differentiationNASbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedNASbiological_process
GO:0046641Positive regulation of alpha-beta T cell proliferationIEAbiological_process
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
GO:0048015Phosphatidylinositol-mediated signalingTASbiological_process
GO:0050731Positive regulation of peptidyl-tyrosine phosphorylationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.82867338630.62816895630.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0544675582
GSE13712_SHEARDown-0.0289479324
GSE13712_STATICDown-0.0464049751
GSE19018Down-0.0523667119
GSE19899_A1Down-0.0488032074
GSE19899_A2Up0.0789317525
PubMed_21979375_A1Up0.0251951072
PubMed_21979375_A2Down-0.0975759124
GSE35957Up0.1744427950
GSE36640Up0.0048720867
GSE54402Down-0.0255122794
GSE9593Up0.1235244307
GSE43922Up0.0175623318
GSE24585Up0.4522804703
GSE37065Down-0.0372211143
GSE28863_A1Down-0.2911098355
GSE28863_A2Down-0.1780615493
GSE28863_A3Up0.0592569692
GSE28863_A4Down-0.0715864470
GSE48662Up0.0703240439

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

AbataceptDB01281 -
GaliximabDB04901 -
BelataceptDB06681 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.