HCSGD entry for GRAP2
1. General information
| Official gene symbol | GRAP2 |
|---|---|
| Entrez ID | 9402 |
| Gene full name | GRB2-related adaptor protein 2 |
| Other gene symbols | GADS GRAP-2 GRB2L GRBLG GRID GRPL GrbX Grf40 Mona P38 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005070 | SH3/SH2 adaptor activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005768 | Endosome | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0007265 | Ras protein signal transduction | TAS | biological_process |
| GO:0007267 | Cell-cell signaling | TAS | biological_process |
| GO:0009967 | Positive regulation of signal transduction | TAS | biological_process |
| GO:0031295 | T cell costimulation | TAS | biological_process |
| GO:0038095 | Fc-epsilon receptor signaling pathway | TAS | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0050852 | T cell receptor signaling pathway | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7615270658 | 0.8021458455 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0887677771 |
| GSE13712_SHEAR | Down | -0.1649638572 |
| GSE13712_STATIC | Up | 0.1748328420 |
| GSE19018 | Up | 0.0180815478 |
| GSE19899_A1 | Up | 0.0555824505 |
| GSE19899_A2 | Up | 0.1723165528 |
| PubMed_21979375_A1 | Up | 0.0155020104 |
| PubMed_21979375_A2 | Up | 0.0027828835 |
| GSE35957 | Up | 0.0975706048 |
| GSE36640 | Down | -0.0122170955 |
| GSE54402 | Up | 0.0056060759 |
| GSE9593 | Up | 0.0134793931 |
| GSE43922 | Up | 0.0095511466 |
| GSE24585 | Up | 0.0418912455 |
| GSE37065 | Down | -0.0592042412 |
| GSE28863_A1 | Down | -0.0446853809 |
| GSE28863_A2 | Down | -0.1735531037 |
| GSE28863_A3 | Up | 0.0993839094 |
| GSE28863_A4 | Up | 0.0952815957 |
| GSE48662 | Down | -0.0322338707 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
