HCSGD entry for PIGS
1. General information
| Official gene symbol | PIGS |
|---|---|
| Entrez ID | 94005 |
| Gene full name | phosphatidylinositol glycan anchor biosynthesis, class S |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003923 | GPI-anchor transamidase activity | IEA TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006501 | C-terminal protein lipidation | TAS | biological_process |
| GO:0016255 | Attachment of GPI anchor to protein | IEA TAS | biological_process |
| GO:0042765 | GPI-anchor transamidase complex | IEA TAS | cellular_component |
| GO:0043687 | Post-translational protein modification | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4366759622 | 0.0658463470 | 0.9999902473 | 0.4843884013 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1732204352 |
| GSE13712_SHEAR | Down | -0.8841046771 |
| GSE13712_STATIC | Down | -0.3269000186 |
| GSE19018 | Up | 0.4755373020 |
| GSE19899_A1 | Down | -0.5180373663 |
| GSE19899_A2 | Down | -0.5282427462 |
| PubMed_21979375_A1 | Down | -0.4955338404 |
| PubMed_21979375_A2 | Down | -0.6490839170 |
| GSE35957 | Down | -0.1701829674 |
| GSE36640 | Up | 0.6169065983 |
| GSE54402 | Down | -0.4267821228 |
| GSE9593 | Down | -0.0657075359 |
| GSE43922 | Down | -0.5271358876 |
| GSE24585 | Up | 0.3885284821 |
| GSE37065 | Down | -0.0598647059 |
| GSE28863_A1 | Up | 0.1996706598 |
| GSE28863_A2 | Up | 0.2433560612 |
| GSE28863_A3 | Up | 0.5283503521 |
| GSE28863_A4 | Up | 0.0133236473 |
| GSE48662 | Up | 0.1791423160 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023832 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-941 | MIMAT0004984 | MIRT036573 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT037030 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043511 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049567 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT050805 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051472 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-3157-5p | MIMAT0015031 | MIRT052667 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
