HCSGD entry for GRHPR
1. General information
| Official gene symbol | GRHPR |
|---|---|
| Entrez ID | 9380 |
| Gene full name | glyoxylate reductase/hydroxypyruvate reductase |
| Other gene symbols | GLXR GLYD PH2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005782 | Peroxisomal matrix | TAS | cellular_component |
| GO:0005829 | Cytosol | IEA | cellular_component |
| GO:0007588 | Excretion | IMP | biological_process |
| GO:0008152 | Metabolic process | NAS | biological_process |
| GO:0008465 | Glycerate dehydrogenase activity | IDA | molecular_function |
| GO:0016616 | Oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | IEA | molecular_function |
| GO:0016618 | Hydroxypyruvate reductase activity | IDA | molecular_function |
| GO:0030267 | Glyoxylate reductase (NADP) activity | IDA NAS | molecular_function |
| GO:0031406 | Carboxylic acid binding | IEA | molecular_function |
| GO:0034641 | Cellular nitrogen compound metabolic process | TAS | biological_process |
| GO:0042803 | Protein homodimerization activity | IDA | molecular_function |
| GO:0043648 | Dicarboxylic acid metabolic process | IEA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046487 | Glyoxylate metabolic process | TAS | biological_process |
| GO:0048037 | Cofactor binding | IEA | molecular_function |
| GO:0051259 | Protein oligomerization | IDA | biological_process |
| GO:0051287 | NAD binding | IEA TAS | molecular_function |
| GO:0055114 | Oxidation-reduction process | IDA | biological_process |
| GO:0070402 | NADPH binding | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8761678774 | 0.0618163406 | 0.9999902473 | 0.4691660611 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0116457938 |
| GSE13712_SHEAR | Down | -0.4779613389 |
| GSE13712_STATIC | Down | -0.2968351568 |
| GSE19018 | Up | 0.0069047271 |
| GSE19899_A1 | Down | -0.8156061003 |
| GSE19899_A2 | Down | -0.2444338042 |
| PubMed_21979375_A1 | Down | -0.6149979348 |
| PubMed_21979375_A2 | Down | -0.6928127837 |
| GSE35957 | Up | 0.0671749894 |
| GSE36640 | Up | 0.3550982758 |
| GSE54402 | Down | -0.1179454370 |
| GSE9593 | Up | 0.0523884432 |
| GSE43922 | Down | -0.2768771559 |
| GSE24585 | Up | 0.0155883675 |
| GSE37065 | Down | -0.0417809664 |
| GSE28863_A1 | Down | -0.0117465279 |
| GSE28863_A2 | Down | -0.2927178734 |
| GSE28863_A3 | Down | -0.3445327638 |
| GSE28863_A4 | Up | 0.4190987063 |
| GSE48662 | Up | 0.1084046575 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1180-3p | MIMAT0005825 | MIRT035939 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040697 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
