HCSGD entry for SLC9A3R2
1. General information
| Official gene symbol | SLC9A3R2 |
|---|---|
| Entrez ID | 9351 |
| Gene full name | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| Other gene symbols | E3KARP NHE3RF2 NHERF-2 NHERF2 OCTS2 SIP-1 SIP1 TKA-1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005102 | Receptor binding | IPI | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006461 | Protein complex assembly | TAS | biological_process |
| GO:0008013 | Beta-catenin binding | IPI | molecular_function |
| GO:0008022 | Protein C-terminus binding | IPI | molecular_function |
| GO:0012505 | Endomembrane system | IEA | cellular_component |
| GO:0014067 | Negative regulation of phosphatidylinositol 3-kinase signaling | IEA | biological_process |
| GO:0016324 | Apical plasma membrane | IEA | cellular_component |
| GO:0019902 | Phosphatase binding | IEA IPI | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2678748642 | 0.1953429467 | 0.9650608130 | 0.8564465523 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0062589591 |
| GSE13712_SHEAR | Up | 0.6785503315 |
| GSE13712_STATIC | Down | -0.7032550557 |
| GSE19018 | Down | -0.0141183729 |
| GSE19899_A1 | Down | -0.2061965128 |
| GSE19899_A2 | Up | 0.3629522588 |
| PubMed_21979375_A1 | Up | 0.1618304122 |
| PubMed_21979375_A2 | Down | -0.2820513879 |
| GSE35957 | Up | 0.1182529603 |
| GSE36640 | Up | 0.1614034805 |
| GSE54402 | Down | -0.3108607919 |
| GSE9593 | Up | 0.3843257292 |
| GSE43922 | Down | -0.1641789410 |
| GSE24585 | Down | -0.0491643350 |
| GSE37065 | Up | 0.0783050046 |
| GSE28863_A1 | Down | -0.3299053512 |
| GSE28863_A2 | Down | -0.2864170873 |
| GSE28863_A3 | Up | 0.3353342528 |
| GSE28863_A4 | Up | 0.1401200771 |
| GSE48662 | Up | 0.0840025519 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30a-5p | MIMAT0000087 | MIRT005146 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020575 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT045974 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
