HCSGD entry for TAOK2

1. General information

Official gene symbolTAOK2
Entrez ID9344
Gene full nameTAO kinase 2
Other gene symbolsMAP3K17 PSK PSK1 PSK1-BETA TAO1 TAO2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000186Activation of MAPKK activityIDAbiological_process
GO:0001558Regulation of cell growthNASbiological_process
GO:0004674Protein serine/threonine kinase activityIDAmolecular_function
GO:0004709MAP kinase kinase kinase activityIBAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005856CytoskeletonIEAcellular_component
GO:0006612Protein targeting to membraneNASbiological_process
GO:0006915Apoptotic processNASbiological_process
GO:0006950Response to stressIDAbiological_process
GO:0006974Cellular response to DNA damage stimulusIDAbiological_process
GO:0008360Regulation of cell shapeIDAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016023Cytoplasmic membrane-bounded vesicleIDAcellular_component
GO:0016477Cell migrationNASbiological_process
GO:0030036Actin cytoskeleton organizationIDAbiological_process
GO:0030425DendriteIEAcellular_component
GO:0030659Cytoplasmic vesicle membraneIEAcellular_component
GO:0031434Mitogen-activated protein kinase kinase bindingIPImolecular_function
GO:0031572G2 DNA damage checkpointIMPbiological_process
GO:0032874Positive regulation of stress-activated MAPK cascadeIMPbiological_process
GO:0043235Receptor complexIDAcellular_component
GO:0046330Positive regulation of JNK cascadeIDAbiological_process
GO:0048041Focal adhesion assemblyIDAbiological_process
GO:0051403Stress-activated MAPK cascadeIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.17770435770.86962206600.82671505571.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1724901009
GSE13712_SHEARDown-0.1255176453
GSE13712_STATICUp0.0132753930
GSE19018Down-0.1689533674
GSE19899_A1Up0.0370793342
GSE19899_A2Up0.2858611886
PubMed_21979375_A1Up0.5708664882
PubMed_21979375_A2Up0.5970928733
GSE35957Down-0.1929775052
GSE36640Up0.2802061672
GSE54402Up0.0831247200
GSE9593Up0.1192458407
GSE43922Up0.0995017614
GSE24585Down-0.0432685258
GSE37065Up0.0280114329
GSE28863_A1Down-0.1204047376
GSE28863_A2Up0.2701753736
GSE28863_A3Down-0.6493916936
GSE28863_A4Up0.0706182287
GSE48662Up0.4853540903

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

PhosphonoserineDB04522 EXPT02883

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-769-5pMIMAT0003886MIRT016093SequencingFunctional MTI (Weak)20371350
hsa-miR-484MIMAT0002174MIRT042035CLASHFunctional MTI (Weak)23622248
hsa-miR-331-3pMIMAT0000760MIRT043319CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049049CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.