HCSGD entry for CD22

1. General information

Official gene symbolCD22
Entrez ID933
Gene full nameCD22 molecule
Other gene symbolsSIGLEC-2 SIGLEC2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005887Integral component of plasma membraneIEAcellular_component
GO:0007155Cell adhesionIEAbiological_process
GO:0009897External side of plasma membraneIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.64802714560.60272138600.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0501825827
GSE13712_SHEARDown-0.0999130374
GSE13712_STATICUp0.0579125421
GSE19018Up0.1026469067
GSE19899_A1Down-0.1619113459
GSE19899_A2Up0.0911886942
PubMed_21979375_A1Up0.2897213874
PubMed_21979375_A2Up0.0516330899
GSE35957Up0.0231697607
GSE36640Down-0.0165606214
GSE54402Up0.1756583012
GSE9593Up0.0411592976
GSE43922Up0.4479484057
GSE24585Down-0.1267870117
GSE37065Down-0.0100700284
GSE28863_A1Down-0.3965791675
GSE28863_A2Down-0.4380976789
GSE28863_A3Up0.1845947265
GSE28863_A4Up0.0096228961
GSE48662Up0.0241284380

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

EpratuzumabDB04958 -

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017296MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.