HCSGD entry for TRIP12
1. General information
| Official gene symbol | TRIP12 |
|---|---|
| Entrez ID | 9320 |
| Gene full name | thyroid hormone receptor interactor 12 |
| Other gene symbols | ULF |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004842 | Ubiquitin-protein ligase activity | IBA IDA IEA IMP | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IBA | cellular_component |
| GO:0005654 | Nucleoplasm | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IBA | cellular_component |
| GO:0006281 | DNA repair | IEA | biological_process |
| GO:0006974 | Cellular response to DNA damage stimulus | IMP | biological_process |
| GO:0009790 | Embryo development | IEA ISS | biological_process |
| GO:0042787 | Protein ubiquitination involved in ubiquitin-dependent protein catabolic process | IBA IDA IMP | biological_process |
| GO:0046966 | Thyroid hormone receptor binding | IDA | molecular_function |
| GO:1901315 | Negative regulation of histone H2A K63-linked ubiquitination | IMP | biological_process |
| GO:2000780 | Negative regulation of double-strand break repair | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1327670415 | 0.3391961590 | 0.7378309835 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4504962594 |
| GSE13712_SHEAR | Down | -0.0025765642 |
| GSE13712_STATIC | Up | 0.0843814052 |
| GSE19018 | Down | -0.3926685020 |
| GSE19899_A1 | Down | -0.0715280863 |
| GSE19899_A2 | Down | -0.0548130809 |
| PubMed_21979375_A1 | Up | 0.1955809354 |
| PubMed_21979375_A2 | Up | 0.5094233860 |
| GSE35957 | Up | 0.2587509512 |
| GSE36640 | Up | 0.2057196993 |
| GSE54402 | Up | 0.1216764660 |
| GSE9593 | Down | -0.0919650441 |
| GSE43922 | Up | 0.1704762296 |
| GSE24585 | Up | 0.3748177813 |
| GSE37065 | Up | 0.0838539608 |
| GSE28863_A1 | Up | 0.6522969995 |
| GSE28863_A2 | Up | 0.7855659179 |
| GSE28863_A3 | Down | -0.7803418002 |
| GSE28863_A4 | Down | -0.3738103047 |
| GSE48662 | Up | 0.0414450300 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022779 | Proteomics | Functional MTI (Weak) | 18668037 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028570 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032415 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040237 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-18a-3p | MIMAT0002891 | MIRT040856 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041560 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-106b-5p | MIMAT0000680 | MIRT044332 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045482 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049069 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
